ArticleRevista da Associacao Medica Brasileira (1992)2026
Comparison of serum ınflammatory parameters between spontaneous abortion and threatened abortion.
Article in Revista da Associacao Medica Brasileira (1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEarly pregnancy loss is a frequent reproductive health problem. Systemic inflammatory markers derived from complete blood count-neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic inflammatory index-may reflect the inflammatory status present at clinical presentation. The aim of this study was to compare these indices between spontaneous abortion and threatened abortion.
methodsThis retrospective cross-sectional study included 146 women evaluated between January 2022 and April 2025. Patients were classified as spontaneous abortion (n=67) or threatened abortion (n=79) based on clinical and ultrasonographic findings. neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic inflammatory index were calculated from complete blood counts. Group comparisons were performed using the Student's t-test or the Mann-Whitney U test. Blood samples were obtained at presentation, when the diagnosis of spontaneous abortion or threatened abortion had already been established; therefore, markers reflected concurrent inflammatory status rather than pre-diagnostic levels.
resultsThe groups were similar regarding age, body mass index, gravida, parity, and gestational age (all p>0.05). Compared with threatened abortion, spontaneous abortion patients had significantly higher white blood cell and neutrophil counts, neutrophil-to-lymphocyte ratio, C-reactive protein, and systemic inflammatory index (all p<0.05). Although platelet-to-lymphocyte ratio values were numerically higher in the spontaneous abortion group, the difference was borderline and not statistically significant (p=0.058).
conclusionSpontaneous abortion is associated with a stronger systemic inflammatory profile at presentation. Elevated systemic inflammatory index, neutrophil-to-lymphocyte ratio, and C-reactive protein levels reflect concurrent inflammation rather than definitive predictive or causal relationships.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.