In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Zilu LiState Key Laboratory of Advanced Drug Delivery and Release Systems, Institute of Pharmaceutics, School of Pharmacy, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0006-1643-6222 Jie QinDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.ORCID 0009-0008-1249-9642 Jiayu ZhangState Key Laboratory of Advanced Medicals and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.ORCID 0009-0005-3665-8431 Yumiao ChenState Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, Shandong University, Jinan 250012, China.ORCID 0000-0002-0501-8424 Daohan YuDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Yiran ZhangState Key Laboratory of Advanced Drug Delivery and Release Systems, Institute of Pharmaceutics, School of Pharmacy, Zhejiang University, Hangzhou 310058, China.
Shengfei YangState Key Laboratory of Advanced Drug Delivery and Release Systems, Institute of Pharmaceutics, School of Pharmacy, Zhejiang University, Hangzhou 310058, China.
Zhuoting LiState Key Laboratory of Advanced Drug Delivery and Release Systems, Institute of Pharmaceutics, School of Pharmacy, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0006-8106-0460 Juanjuan ZhengState Key Laboratory of Advanced Drug Delivery and Release Systems, Institute of Pharmaceutics, School of Pharmacy, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-5360-2249 Jinquan CaiDepartment of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.ORCID 0000-0002-6773-3546 Fan HuangState Key Laboratory of Advanced Medicals and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China.ORCID 0000-0001-9029-8805 Jianqing GaoState Key Laboratory of Advanced Drug Delivery and Release Systems, Institute of Pharmaceutics, School of Pharmacy, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0003-1052-7060 Yu ZhaoState Key Laboratory of Advanced Drug Delivery and Release Systems, Institute of Pharmaceutics, School of Pharmacy, Zhejiang University, Hangzhou 310058, China.ORCID 0009-0000-5444-4078 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Lipid nanoparticles (LNPs), composed of ionizable lipids, phospholipids, cholesterol, and PEGylated lipids, have been successfully used in messenger RNA (mRNA) vaccine development. Despite substantial progress, endosomal entrapment after cellular internalization is still a critical bottleneck limiting the vaccine efficacy. While the efforts to optimize lipid p
Indexed as
EndosomesLipidsNanoparticlesRNA, MessengerAnimalsCancer VaccinesHumansLiposomesCancer VaccinesLipid NanoparticlesLipidsLiposomesRNA, Messenger
Identifiers
PMID42384808
PMCPMC13322231
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