Evidence map›Paper›PMID 42384803›Full record

ArticleScience advances2026

Dimer asymmetry in signaling of blue light sensor histidine kinases.

Vladimir Arinkin, Andreas M Stadler, Stefanie S M Meier, Karl-Erich Jaeger, Andreas Möglich, Ulrich Krauss, Renu Batra-Safferling

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vladimir ArinkinInstitut für Biologische Informationsprozesse (IBI), Strukturbiochemie (IBI-7), Forschungszentrum Jülich, 52425 Jülich, Germany.ORCID 0000-0002-9210-9366
Andreas M StadlerNeutron Scattering and Soft Matter (JCNS-1), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.ORCID 0000-0003-2272-5232
Stefanie S M MeierDepartment of Biochemistry, University of Bayreuth, 95447 Bayreuth, Germany.ORCID 0009-0002-6028-5223
Karl-Erich JaegerInstitut für Molekulare Enzymtechnologie, Heinrich-Heine-Universität Düsseldorf, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.ORCID 0000-0002-6036-0708
Andreas MöglichDepartment of Biochemistry, University of Bayreuth, 95447 Bayreuth, Germany.ORCID 0000-0002-7382-2772
Ulrich KraussDepartment of Biochemistry, University of Bayreuth, 95447 Bayreuth, Germany.ORCID 0000-0003-2219-7388
Renu Batra-SafferlingInstitut für Biologische Informationsprozesse (IBI), Strukturbiochemie (IBI-7), Forschungszentrum Jülich, 52425 Jülich, Germany.ORCID 0000-0002-8597-4335

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoreceptor sensory histidine kinases (SHKs) couple light absorption to conformational changes regulating two-component signaling. Despite their importance and widespread use in optogenetics, the underlying structural signaling mechanisms remain poorly understood. Here, we engineered dimeric SHKs based on

Indexed as

Bacterial ProteinsHistidine KinaseProtein MultimerizationPseudomonas putidaSignal TransductionBlue LightCrystallography, X-RayLightModels, MolecularProtein ConformationBacterial ProteinsHistidine Kinase

Identifiers

PMID42384803
PMCPMC13322254

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.