Evidence map›Paper›PMID 42384788›Full record

ArticleScience advances2026

Loss of O-antigen due to

Kaleb J Tyson, Amanda Z Velez, Blake M Hanson, Jianping Jiang, Kuan-Yi Lu, Felicia Ruffin, Granger Sutton, Lauren M Brinkac, Thomas H Clarke, Yazhong Tao and 8 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kaleb J TysonDivision of Infectious Diseases, Duke University School of Medicine, Durham, NC 27710, USA.ORCID 0009-0002-7415-2405
Amanda Z VelezDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27559, USA.ORCID 0000-0001-7007-7394
Blake M HansonCenter for Infectious Diseases, University of Texas Health Science Center, Houston, TX 77030, USA.ORCID 0000-0003-2949-7818
Jianping JiangCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA.ORCID 0000-0002-1066-6362
Kuan-Yi LuDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27559, USA.ORCID 0000-0002-3663-377X
Felicia RuffinDivision of Infectious Diseases, Duke University School of Medicine, Durham, NC 27710, USA.
Granger SuttonJ. Craig Venter Institute, Rockville, MD 20850, USA.ORCID 0000-0001-7498-8048
Lauren M BrinkacJ. Craig Venter Institute, Rockville, MD 20850, USA.
Thomas H ClarkeJ. Craig Venter Institute, Rockville, MD 20850, USA.ORCID 0000-0002-1916-1029
Yazhong TaoDivision of Infectious Diseases, Duke University School of Medicine, Durham, NC 27710, USA.
Derrick E FoutsJ. Craig Venter Institute, Rockville, MD 20850, USA.ORCID 0000-0003-4323-7668
Mark D AdamsJ. Craig Venter Institute, Rockville, MD 20850, USA.ORCID 0000-0003-3161-7460
Cesar A AriasDivision of Infectious Diseases, Houston Methodist Hospital and Center for Infectious Diseases, Houston Methodist Research Institute, Houston, TX 77030, USA.ORCID 0000-0001-9054-9774
Sanjay KhandelwalDivision of Hematology, Duke University Medical Center, Durham, NC 27710, USA.ORCID 0000-0002-5661-3856
Vance G FowlerDivision of Infectious Diseases, Duke University School of Medicine, Durham, NC 27710, USA.ORCID 0000-0002-8048-0897
Joshua T ThadenDivision of Infectious Diseases, Duke University School of Medicine, Durham, NC 27710, USA.ORCID 0000-0002-3250-0697
Brian P ConlonDepartment of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27559, USA.ORCID 0000-0002-2155-8375
Joshua B ParsonsDivision of Infectious Diseases, Duke University School of Medicine, Durham, NC 27710, USA.ORCID 0000-0002-0589-3587

Funding

Microbial Genomic Determinants of Antibiotic Treatment Failure in Staphylococcus aureus BacteremiaK08AI187747 · NIAID · DUKE UNIVERSITY · PI Joshua B Parsons · 2025 to 2026
$380k
NIAID NIH HHS K08 AI187747
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BacteremiaEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsMutationO AntigensAnimalsDisease Models, AnimalHumansLipopolysaccharidesMiceEscherichia coli ProteinsLipopolysaccharidesO Antigens

Identifiers

PMID42384788
PMCPMC13322237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.