Evidence map›Paper›PMID 42384656›Full record

ArticlePloS one2026

Probability of a timely vocal response in mother-infant interaction and later psychiatric diagnosis: A case-control study.

Bethany Stanley, Clare S Allely, Jenna Charlton, Christopher Gillberg, James Law, Penny Levickis, Alex McConnachie, Christine Puckering, Lucy Thompson, Philip Wilson

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bethany StanleyRobertson Centre for Biostatistics, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.ORCID https://orcid.org/0000-0003-3299-4014
Clare S AllelySchool of Health and Society, Centre for Applied Health Research, University of Salford, Salford, United Kingdom.ORCID https://orcid.org/0000-0001-7640-9505
Jenna CharltonSchool of Education, Communication and Language Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Christopher GillbergGillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
James LawSchool of Education, Communication and Language Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.
Penny LevickisREEaCh Centre, Faculty of Education, The University of Melbourne, Melbourne, Victoria, Australia.
Alex McConnachieRobertson Centre for Biostatistics, School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
Christine PuckeringDepartment of Child and Adolescent Psychiatry, School of Health and Wellbeing, Royal Hospital for Sick Children, Glasgow, United Kingdom.
Lucy ThompsonGillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Philip WilsonInstitute of Applied Health Sciences, University of Aberdeen, Inverness, United Kingdom.ORCID https://orcid.org/0000-0002-4123-8248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patterns of parent-child interactions are commonly cited as being predictive of later psychiatric disorders but precisely which elements of these interactions are important is rarely clear, potentially affecting the effective targeting of interventions in young children. The current study aimed to examine the relationship between timely vocal response during parent-child interactions (i.e., the probability of mothers responding to their child within a specified time period and vice versa), and later psychiatric diagnosis. Drawing on data from the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort, a case control study was conducted based on infant-mother video observations of children assessed for neuropsychiatric disorders using the parent-reported Development and Wellbeing Assessment (DAWBA) at seven years of age (103 controls and 55 cases). Empirical examination suggested that 1 second represented the optimal threshold for maternal responses and 8 seconds for child responses. Only the maternal measure was found to predict later psychiatric disorders, with evidence of associations limited to hyperactivity and conduct disorders. These associations were not sensitive to either maternal education or child sex. The results are discussed in terms of the value of precise interpretation of early mother/child interaction and for the potential for providing targeted intervention to the population concerned.

Indexed as

Mental DisordersMother-Child RelationsCase-Control StudiesChildFemaleHumansInfantLongitudinal StudiesMaleMothers

Identifiers

PMID42384656
PMCPMC13322543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.