Evidence map›Paper›PMID 42384191›Full record

ArticlePediatric radiology2026

The radiographic bubbly fecal pattern of intestinal pneumatosis in newborns revisited.

Magdalena Sophie Schmidt, Ina Bettzieche, Michael Zellner, Christian J Kellenberger, Irmhild Altmann-Schneider

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Magdalena Sophie SchmidtDepartment of Diagnostic Imaging, University Children's Hospital Zurich, Zurich, Switzerland. magdalena.schmidt@sickkids.ca.
Ina BettziecheDepartment of Diagnostic Imaging, University Children's Hospital Zurich, Zurich, Switzerland.
Michael ZellnerDepartment of Diagnostic Imaging, University Children's Hospital Zurich, Zurich, Switzerland.
Christian J KellenbergerDepartment of Diagnostic Imaging, University Children's Hospital Zurich, Zurich, Switzerland.
Irmhild Altmann-SchneiderDepartment of Diagnostic Imaging, University Children's Hospital Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA bubbly fecal pattern on abdominal radiographs of neonates was described in the 1980s as a potential sign of intestinal pneumatosis, particularly in preterm infants during the first 2 weeks of life. This sign has not been systematically re-evaluated or correlated with sonographic findings.

objectiveTo assess whether, and up to which age, a radiographic bubbly fecal pattern represents intestinal pneumatosis, using bowel ultrasound as the reference standard. MATERIALS AND

methodsInfants aged 0-97 days who underwent abdominal radiography and bowel ultrasound for suspected ischemic enterocolitis in the neonatal intensive care unit were retrospectively included between January 2012 and December 2023. Radiography and ultrasound had to be performed within 24 h of each other. Imaging findings were analyzed per patient and per imaging episode.

resultsA total of 191 infants (82 female) were included, resulting in 402 paired examinations. Median age at imaging was 18 days. A bubbly fecal pattern was identified on 212 radiographs in 119 infants, with sonographic intestinal pneumatosis present in 172 cases (81.1%). Positive predictive values were consistently high, reaching 80.7% overall, while specificity and negative predictive values remained low across all age groups. A negative ultrasound in the presence of a bubbly fecal pattern was associated with a low surgical rate (6.5%). Sonographic pneumatosis was present in 90% of infants who underwent surgery.

conclusionIn infants evaluated for suspected necrotizing/ischemic enterocolitis, a radiographic bubbly fecal pattern is a relevant imaging sign associated with intestinal pneumatosis, particularly during the first 8 weeks of life.

Indexed as

Enterocolitis, necrotizingInfant, newbornRadiography, abdominalRetrospective studiesUltrasonography

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.