Evidence map›Paper›PMID 42384182›Full record

SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2026

Contemporary bicruciate-retaining total knee arthroplasty implants demonstrate favorable survivorship: a systematic review and meta-analysis of 1576 knees.

Varun Kompala, Khaled A Elmenawi, Maile Wedgwood, Islam A Sherif, Loren Hackett, Michael S Ramos, Adolph V Lombardi, Nicolas S Piuzzi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Varun KompalaDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Khaled A ElmenawiDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Maile WedgwoodDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Islam A SherifDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Loren HackettFloyd D. Loop Alumni Library, Cleveland Clinic, Cleveland, OH, USA.
Michael S RamosDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
Adolph V LombardiJoint Implant Surgeons, Inc., New Albany, OH, USA.
Nicolas S PiuzziDepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA. piuzzin@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBicruciate-retaining (BCR) total knee arthroplasty (TKA) was developed to better replicate native knee biomechanics by preserving both cruciate ligaments. First-generation BCR implants were notorious for technical challenges and suboptimal survivorship. However, advancements in implant design and surgical techniques have renewed interest in second-generation BCR TKA systems. This study aimed to evaluate the overall survivorship of contemporary (second-generation) BCR primary TKA implants.

methodsA systematic review of PubMed, Scopus, Embase, Web of Science, and Cochrane databases was conducted from inception to January 3, 2025. Inclusion criteria were studies that reported the number of revisions following second-generation BCR TKA. We excluded case reports, review articles, and studies that evaluated first-generation BCR TKA. A total of 1046 articles were retrieved; ultimately, 13 were included. Events per person-years pooled analysis was performed to estimate the incidence of all-cause revision, adjusting for duration of follow-up. Heterogeneity was measured using I

resultsA total of 1,087 BCR TKA implants among 13 studies were analyzed. The mean follow-up was 2.6 years. A total of 62 (5.7%) knees were revised. The overall pooled rate of all-cause revision was 1.6 per 100 person-years (95% confidence interval [CI] 0.009-0.023) Heterogeneity among the analyzed studies was significant (I

conclusionContemporary BCR TKA implants showed improved survivorship compared to historical reports, with a low pooled all-cause revision rate of 1.6 per 100 person-years, corresponding to a 1.6% chance of revision per year of follow-up. Despite the associated heterogeneity, these findings suggest that modern BCR designs offer durable outcomes and support their continued use. Further long-term comparative data are needed to better define their role relative to modern knee implants.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisHumansProsthesis DesignProsthesis FailureReoperationBicruciateBiomechanicsSurvivorshipTKATotal knee arthroplasty

Identifiers

PMID42384182
PMCPMC13323789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.