Evidence map›Paper›PMID 42384161›Full record

ArticleProbiotics and antimicrobial proteins2026

Antimicrobial Mechanism of Temporin L Peptide Against Bacillus cereus from Fermented Sausage.

Tiantian Yu, Fangyu Wang, Ibrahim A Bakry, Qian Li, Tiange Li, Guangshan Zhao, Yongxia Cheng, Peijun Zhao, Mei Hu, Lianjun Song and 5 more

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tiantian YuCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Fangyu WangHenan Provincial Academy of Fishery Sciences, No. 48 Jiangshan Road, Huiji District, Zhengzhou, 450048, China.
Ibrahim A BakryCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Qian LiCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Tiange LiCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Guangshan ZhaoCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Yongxia ChengCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Peijun ZhaoCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Mei HuCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Lianjun SongCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Bangbang ZhaoCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Xianqing HuangCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China.
Gianni GalavernaFood and Drug Department, University of Parma, Parco Area delle Scienze, 17/a, Parma, 43124, Italy.
Yue ShenCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China. yueshen@henau.edu.cn.
Ning LiCollege of Food Science and Technology, Henan Agricultural University, 63#Agricultural Road, Zhengzhou, 450000, China. ln8028@163.com.

Funding

Excellent Youth Project of the Natural Science Foundation of Henan Province 202300410193Henan Center for Outstanding Overseas Scientists GZS2025010National Natural Science Foundation of China 31201878, U1204804, U1604183the 2022 Henan Graduate Joint Training Base Project YJS2022JD16the Henan Province Key Research and Development Program 241111110600the Henan Provincial University Science and Technology Innovation Team Support Program 23IRTSTHN023
6 · The paper itself

Abstract

Bacillus cereus (B. cereus) is a prevalent foodborne pathogen. This study evaluated the antimicrobial efficacy and mechanism of the peptide Temporin L against B. cereus. Quantitative assays showed that Temporin L had a minimum inhibitory concentration (MIC) of 8 µM and a minimum bactericidal concentration (MBC) of 16 µM. Complete bacterial eradication occurred within 1 h at 2 MIC, and complete inhibition was observed within 24 h at MIC and 2 MIC. The peptide retained over 90% antibacterial activity under ultraviolet (UV) light, at high temperatures (up to 100 °C), and under various metal-ion conditions, with Fe ions reducing activity to 82.11%. Membrane integrity assays indicated concentration-dependent increases in PI fluorescence (1.9-2.4 fold) and in leakage of intracellular biomolecules. Metabolic enzyme activities (NaK-ATPase, SDH, LDH) and intracellular ATP levels were significantly reduced, with SDH and LDH dropping from ~ 39/43 to ~ 10 U/mg protein after 1 h at 2 MIC. Oxidative stress markers showed elevated ROS, decreased antioxidant capacity, increased lipid peroxidation, and reduced SOD activity, confirming the multifaceted bacterial damage mechanism induced by Temporin L.

Indexed as

Antimicrobial peptideFoodborne pathogenFood safetyTemporin L

Identifiers

PMID42384161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.