Evidence map›Paper›PMID 42384147›Full record

ArticleSports medicine - open2026

Prevalence and Clinical Significance of Short PR Interval in 1310 Children and Adolescent Athletes: A Cross-Sectional Study.

Klara Komici, Antonio Dello Iacono, Luigi Aversa, Grazia Daniela Femminella, Giuseppe Rengo, Germano Guerra

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Article in Sports medicine - open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Klara KomiciDepartment of Medicine and Health Sciences, University of Molise, 86100, Campobasso, Italy. klara.komici@unimol.it.ORCID http://orcid.org/0000-0001-9419-2426
Antonio Dello IaconoSport and Physical Activity Research Institute (SPARI), Division of Sport, Exercise and Health, School of Health and Life Sciences, University of the West of Scotland, Glasgow, UK.
Luigi AversaDepartment of Medicine and Health Sciences, University of Molise, 86100, Campobasso, Italy.
Grazia Daniela FemminellaDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Giuseppe RengoDepartment of Translational Medical Sciences, University of Naples "Federico II", Naples, Italy.
Germano GuerraDepartment of Medicine and Health Sciences, University of Molise, 86100, Campobasso, Italy.

Funding

Toursitfit SA-0300562
6 · The paper itself

Abstract

backgroundChildren and adolescents represent a challenging population due to their incomplete physical development, and lack of specific criteria for interpreting electrocardiography (ECG) in children and adolescent athletes. We aimed to investigate the prevalence and clinical significance of short PR interval in pediatric and adolescent athletes undergoing pre-participation cardiac screening.

methodsThis is a cross-sectional study, where a total of 1310 athletes (age range: 7-18 years) underwent a comprehensive screening including medical history, physical examination, 12-lead ECG, echocardiography, and exercise testing under stress at Exercise and Sports Medicine Unit, University of Molise, Campobasso Italy between January 2023 and June 2024. Short PR interval prevalence and clinical significance were evaluated by frequency analysis and association with cardiac symptoms, respectively.

resultsShort PR interval (< 120 ms) was present in 26.9% of athletes, while using a z-score threshold of - 2 as the age- and sex-adjusted lower limit of normal, 3.82% of the athletes met criteria for a short PR interval. No significant associations were found between short PR interval and cardiac symptoms: syncope, palpitations, chest pain, exercise-induced arrhythmias, or need for additional diagnostic testing beyond standard screening (p > 0.05).

conclusionsIsolated short PR interval was not associated with adverse cardiac findings among children and adolescent athletes following pre-participation screening, supporting its interpretation as a benign age-dependent variant. However, long-term outcome data are needed to confirm these observations.

Indexed as

Adolescent athletesElectrocardiographyPre-participation screeningShort PR intervalSports cardiology

Identifiers

PMID42384147
PMCPMC13323764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.