In one paragraphArticle in Diabetes care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Kirk R HohsfieldDepartment of Epidemiology, Colorado School of Public Health, University of Colorado-Anschutz, Aurora, CO.ORCID 0000-0002-6707-7913 Fran DongBarbara Davis Center for Diabetes, School of Medicine, University of Colorado-Anschutz, Aurora, CO.
Kathleen WaughBarbara Davis Center for Diabetes, School of Medicine, University of Colorado-Anschutz, Aurora, CO.
Andrea K SteckBarbara Davis Center for Diabetes, School of Medicine, University of Colorado-Anschutz, Aurora, CO.ORCID 0000-0002-5931-9484 Teresa BucknerDepartment of Kinesiology, Nutrition, and Dietetics, University of Northern Colorado, Greeley, CO.ORCID 0000-0002-5831-1683 Randi K JohnsonDepartment of Epidemiology, Colorado School of Public Health, University of Colorado-Anschutz, Aurora, CO.ORCID 0000-0001-9345-4439 Patrick M CarryDepartment of Epidemiology, Colorado School of Public Health, University of Colorado-Anschutz, Aurora, CO.ORCID 0000-0002-2989-7080 Brigitte FrohnertBarbara Davis Center for Diabetes, School of Medicine, University of Colorado-Anschutz, Aurora, CO.ORCID 0000-0002-6636-4048 Marian RewersBarbara Davis Center for Diabetes, School of Medicine, University of Colorado-Anschutz, Aurora, CO.ORCID 0000-0003-3829-9207 Jill M NorrisDepartment of Epidemiology, Colorado School of Public Health, University of Colorado-Anschutz, Aurora, CO.ORCID 0000-0001-8674-2598 Funding
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)U01DK128847 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI JEFFREY P KRISCHER · 2021 to 2026
$79.2MData Coordinating Center (DCC)for the Consortium for Identification of EnvironmenUC4DK095300 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2011 to 2011
$56.0MNIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1MData Coordinating CenterU01DK063790 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2002 to 2006
$50.1MFollow-up on Subjects, Integrative Data Analysis and Measurement of Viral Antibodies in The Environmental Determinants of Diabetes in The Young Study (TEDDY)U01DK124166 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2020 to 2022
$31.1MNIDDK Follow-up on Subjects and Immunological Assessments in The Environmental Determinants of Diabetes In The Young Study (TEDDY) (UC4)UC4DK117483 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2017 to 2020
$30.4MEstablish a Data Coordinating Center (DCC) for the Consortium for Identification UC4DK100238 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2014 to 2014
$28.9MThe Study of Epigenetics and Infections in The Environmental Determinants of Diabetes in the Young (TEDDY)UC4DK112243 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2016 to 2016
$27.0MData Coordinating Center (DCC) for the Consortium for Identification of Environmental Determinants of Diabetes in the Young (TEDDY) StudyUC4DK106955 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI KRISCHER, JEFFREY P · 2015 to 2015
$20.0MThe Environmental Determinants of Diabetes in Young (TEDDY0U01DK063863 · NIDDK · HOSPITAL DISTRICT OF SOUTHWEST FINLAND · PI TOPPARI, JORMA · 2003 to 2022
$13.5MThe Environmental Triggers of Diabetes (TEDDY) in SwedenU01DK063861 · NIDDK · UNIVERSITY OF WASHINGTON · PI LERNMARK, AKE · 2003 to 2022
$13.4MTHE TEDDY STUDY - COLORADO CLINICAL CENTERU01DK063821 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI REWERS, MARIAN J · 2003 to 2022
$12.3MBreakthrough T1D (formerly JDRF)Centers for Disease Control and Prevention (CDC)Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)National Institute of Allergy and Infectious Diseases R21-AI142483National Institute of Environmental Health Sciences (NIEHS)NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR002535NIAID NIH HHS R21 AI142483NIDDK NIH HHS P30 DK116073NIDDK NIH HHS P30-DK116073NIDDK NIH HHS R01 DK032493NIDDK NIH HHS R01 DK104351NIDDK NIH HHS R01-DK104351NIDDK NIH HHS R01-DK32493NIDDK NIH HHS U01 DK063790NIDDK NIH HHS U01 DK063821NIDDK NIH HHS U01 DK063829NIDDK NIH HHS U01 DK063836NIDDK NIH HHS U01 DK063861NIDDK NIH HHS U01 DK063863NIDDK NIH HHS U01 DK063865NIDDK NIH HHS U01 DK124166NIDDK NIH HHS U01 DK128847NIDDK NIH HHS UC4 DK063821NIDDK NIH HHS UC4 DK063829NIDDK NIH HHS UC4 DK063836NIDDK NIH HHS UC4 DK063861NIDDK NIH HHS UC4 DK063863NIDDK NIH HHS UC4 DK063865NIDDK NIH HHS UC4 DK095300NIDDK NIH HHS UC4 DK100238NIDDK NIH HHS UC4 DK106955NIDDK NIH HHS UC4 DK112243NIDDK NIH HHS UC4 DK117483NIH HHS HHSN267200700014CNIH HHS U01 DK124166NIH HHS U01 DK128847NIH HHS U01 DK63790NIH HHS U01 DK63821NIH HHS U01 DK63829NIH HHS U01 DK63836NIH HHS U01 DK63861NIH HHS U01 DK63863NIH HHS U01 DK63865NIH HHS UC4 DK100238NIH HHS UC4 DK106955NIH HHS UC4 DK112243NIH HHS UC4 DK117483NIH HHS UC4 DK63821NIH HHS UC4 DK63829NIH HHS UC4 DK63836NIH HHS UC4 DK63861NIH HHS UC4 DK63863NIH HHS UC4 DK63865NIH HHS UC4 DK95300NLM NIH HHS HHSN267200700014C
6 · The paper itselfAbstract
objectiveWe investigated islet autoimmunity (IA) incidence trends among Colorado children born 1993-2010 in Diabetes Autoimmunity Study in the Young (DAISY) and The Environmental Determinants of Diabetes in the Young (TEDDY) and whether HLA genotype or early-life environmental exposures contributed to observed increases. RESEARCH DESIGN AND
methodsWe analyzed the risk of IA among 2,734 Colorado children representing three birth cohorts (BCs): BC1 (1993-1998), BC2 (1999-August 2004), and BC3 (September 2004-2010). Cox models evaluated IA by BC, with time-varying coefficients, BC-HLA interaction, and stratification by type 1 diabetes family history. Mediation analyses examined age at gluten introduction, weight-for-age Z-score, and maternal smoking.
resultsIA increased across BC1-BC3 (7.0%, 10.7%, and 12.7%). At age 1 year, moderate-risk HLA participants in BC2 and BC3 had, respectively, 2.57 and 6.19 times the IA risk of BC1. By age 5 years, effects attenuated. No selected environmental exposures mediated the increased incidence.
conclusionsIA increased among Colorado children born 1993-2010, with the strongest effects among moderate-risk HLA genotypes in later BCs.
Indexed as
AutoimmunityDiabetes Mellitus, Type 1HLA AntigensIslets of LangerhansChildChild, PreschoolColoradoFemaleGenotypeHumansIncidenceInfantMaleHLA Antigens
Identifiers
PMID42384070
PMCPMC13493339
What OpenQuestion holds
Textmetadata
Read underepoch 390