ArticleAesthetic plastic surgery2026
Clinical Outcomes of HArmonyCa® in South American Patients: A Case Series Using Vectra 3D Technology.
Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
6 authors.
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Abstract
backgroundFacial aging is a complex and multifactorial process that progressively affects the structure, volume, and quality of facial tissues. This study aims to present a case series involving South American patients of different generations and facial morphotypes treated with HArmonyCa®, a hybrid filler composed of hyaluronic acid and calcium hydroxylapatite.
methodsFour patients of varying ages, genders, and facial profiles underwent individualized treatment plans tailored to their aesthetic concerns and aging patterns. All patients received clinical evaluation and three-dimensional imaging analysis using the Vectra 3D system, which enabled precise quantitative assessment of outcomes.
resultsSignificant improvement in facial firmness and contour definition was observed, yielding a rejuvenated, natural-looking appearance. The bio-stimulatory effects of calcium hydroxylapatite, combined with the immediate volumization from hyaluronic acid, produced a noticeable and progressive lifting effect. Three-dimensional imaging supported the clinical findings by demonstrating tissue repositioning and volumetric enhancement in strategic facial areas.
conclusionThis case series highlights the potential of HArmonyCa® as an effective, safe, and versatile approach for facial rejuvenation, adaptable to a wide range of patient profiles. The integration of objective tools such as 3D imaging further enhances treatment planning and outcome evaluation. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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