SynthesisJournal of gastroenterology and hepatology2026
Patient-Level Predictors of Procedural Success in Colon Capsule Endoscopy: A Systematic Review and Meta-Analysis.
Synthesis in Journal of gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColon capsule endoscopy (CCE) is an increasingly used noninvasive alternative to colonoscopy for colonic investigation. However, its widespread adoption is constrained by suboptimal completion rates (CR), inadequate bowel preparation, and a high follow-up endoscopy rate (FER), collectively undermining cost-effectiveness and service efficiency. Evidence on patient-level predictors of these outcomes remains fragmented.
methodsA systematic review and meta-analysis were conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. MEDLINE, Embase, CENTRAL, and PubMed Central were searched. Patient-level factors associated with completion rate, bowel preparation adequacy, successful CCE, and FER were extracted. Random-effects meta-analyses were performed to pool unadjusted and adjusted odds ratios.
resultsTen studies comprising 4374 participants met inclusion criteria. The pooled completion rate was 73% (95% CI 68%-78%), and pooled bowel preparation adequacy was 72% (95% CI 60%-81%). Chronic opioid use was consistently associated with reduced performance, demonstrating lower completion rates (unadjusted OR 0.54, 95% CI 0.40-0.73; adjusted OR 0.55, 95% CI 0.28-1.09) and poorer bowel preparation adequacy (adjusted OR 0.49, 95% CI 0.26-0.96). Diabetes was independently associated with inadequate bowel preparation (adjusted OR 0.40, 95% CI 0.36-0.45). Increasing age showed borderline statistical significance but minimal clinical impact. The pooled follow-up endoscopy rate was 61% (95% CI 56%-67%).
conclusionCCE performance is strongly influenced by patient-level factors, particularly chronic opioid use and diabetes. Targeted patient selection is the most immediately actionable strategy to improve efficiency, whereas individual participant data meta-analyses are needed to enable robust risk stratification of CCE.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.