Evidence map›Paper›PMID 42383926›Full record

ArticleJournal of virology2026

MGF110-2L deletion prevents IFN-I and inflammatory response, resulting in partial attenuation and protection against virulent ASFV.

Julia Gata-de-Benito, Marek Walczak, Lihong Liu, Gonzalo Vigara-Astillero, Krzesimir Szymankiewicz, Maciej Kochanowski, Jacek Żmudzki, Yolanda Revilla, Daniel Pérez-Núñez

Abstract read
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Julia Gata-de-BenitoMicrobes in Health and Welfare Department, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.ORCID 0009-0004-3071-3287
Marek WalczakDepartment of Swine Diseases, National Veterinary Research Institute, Pulawy, Poland.ORCID 0000-0002-2991-9964
Lihong LiuDepartment of Microbiology, Swedish Veterinary Agency, Uppsala, Sweden.ORCID 0000-0002-5921-6805
Gonzalo Vigara-AstilleroMicrobes in Health and Welfare Department, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.ORCID 0000-0003-0933-6400
Krzesimir SzymankiewiczDepartment of Swine Diseases, National Veterinary Research Institute, Pulawy, Poland.
Maciej KochanowskiDepartment of Bacteriology and Bacterial Animal Diseases, National Veterinary Research Institute, Pulawy, Poland.
Jacek ŻmudzkiDepartment of Bacteriology and Bacterial Animal Diseases, National Veterinary Research Institute, Pulawy, Poland.
Yolanda RevillaMicrobes in Health and Welfare Department, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.ORCID 0000-0001-6555-6331
Daniel Pérez-NúñezMicrobes in Health and Welfare Department, Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Madrid, Spain.ORCID 0000-0002-0901-8309

Funding

Agencia Estatal de Investigación PID2023-151591OB-I00National Center for Research and Development ICRAD/I/IFNASF/03/2021Svenska Forskningsrådet Formas 2020-02739
6 · The paper itself

Abstract

African swine fever virus (ASFV) encodes numerous multigene family (MGF) proteins whose individual contributions to virulence and immune modulation remain poorly understood. Here, we characterize the role of MGF110-2L in shaping innate immunity and disease outcome

Indexed as

African Swine FeverAfrican Swine Fever VirusInterferon Type IViral ProteinsVirulence FactorsAnimalsGene DeletionImmunity, InnateInflammationLeukocytes, MononuclearMacrophagesSwineVaccines, AttenuatedVirulenceInterferon Type IVaccines, AttenuatedViral ProteinsVirulence FactorsArm/07/CBM/c2ASFVIFN-IinflammationLAVMGF110-2Lvaccinevirulence

Identifiers

PMID42383926
PMCPMC13386828

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.