Evidence map›Paper›PMID 42383770›Full record

ArticleMicrobiology spectrum2026

Muc16 contributes to protection against invasive pneumococcal infection originating from nasal colonization.

Daichi Murakami, Tatsuya Shiga, Hideki Sakatani, Takuro Iyo, Hiroki Kuwazoe, Kazuya Mizobata, Ryo Ueda, Shizuya Saika, Muneki Hotomi, Masamitsu Kono

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daichi Murakami *Department of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.ORCID 0000-0001-9991-9428
Tatsuya Shiga *Department of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Hideki SakataniDepartment of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Takuro IyoDepartment of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Hiroki KuwazoeDepartment of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Kazuya MizobataDepartment of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Ryo UedaDepartment of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Shizuya SaikaDepartment of Ophthalmology, Wakayama Medical University, Wakayama, Japan.ORCID 0000-0003-1584-9552
Muneki HotomiDepartment of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.ORCID 0000-0003-4705-5319
Masamitsu KonoDepartment of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.ORCID 0000-0002-7896-4892

Funding

Japan Society for the Promotion of Science 23K09653Shionogi Infectious Disease Research Promotion Foundation 2024N086Smoking Research Foundation 2022Y002Smoking Research Foundation 2022Y009
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CA-125 AntigenMembrane ProteinsNasal MucosaPneumococcal InfectionsStreptococcus pneumoniaeAnimalsBacterial LoadDisease Models, AnimalFemaleHumansLungMaleMiceMice, Inbred C57BLMice, KnockoutCA-125 AntigenMembrane ProteinsMUC16 protein, mousecigarette smokeinvasive pneumococcal diseaseMuc16mucosal disruptionStreptococcus pneumoniae

Identifiers

PMID42383770
PMCPMC13435705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.