ArticleThe Journal of international medical research2026
The inflammation-nutrition axis and survival outcomes: Role of the neutrophil percentage-to-albumin ratio in patients with sleep disorders.
Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BackgroundThe neutrophil percentage-to-albumin ratio has shown prognostic significance across several chronic diseases; however, its relevance within the context of sleep disorders has not been investigated.MethodsThis study utilized data from the National Health and Nutrition Examination Survey for the years 2005-2014 to explore the connection between the neutrophil percentage-to-albumin ratio and all-cause mortality in people with sleep disorders. Mortality risk was assessed using Cox regression, and the analyses included restricted cubic spline, Kaplan-Meier survival, subgroup, and time-dependent receiver operating characteristic curve analyses.ResultsA positive correlation was identified between the neutrophil percentage-to-albumin ratio and mortality risk among individuals with sleep disorders (hazard ratio = 1.09, 95% confidence interval: 1.05, 1.14). A comparison between the highest (Q4) and lowest (Q1) quartiles revealed that patients in Q4 had an 86% higher mortality risk (hazard ratio = 1.86, 95% confidence interval: 1.31, 2.65). Subgroup analysis further confirmed consistency across different demographic and clinical strata (all
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