Evidence map›Paper›PMID 42383740›Full record

ArticleJournal of virology2026

A novel monoclonal antibody targeting the hemagglutinin-neuraminidase of peste des petits ruminants virus maintains neutralizing activity by blocking viral adsorption and receptor interaction.

Ruiqi Li, Ashenafi Kiros Wubshet, Shasha Wang, Xiaolong Bai, Lingling Tie, Zaib Ur Rehman, Xiaolong Gao, Huibao Wang, Yu Han, Xiangwei Wang and 4 more

Abstract read
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ruiqi LiCollege of Veterinary Medicine, Xinjiang Agricultural University, Ürümqi, People's Republic of China.
Ashenafi Kiros WubshetShandong Binzhou Institute of Animal Husbandry and Veterinary Sciences, Binzhou, People's Republic of China.ORCID 0000-0002-9008-2075
Shasha WangState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.
Xiaolong BaiCollege of Veterinary Medicine, Xinjiang Agricultural University, Ürümqi, People's Republic of China.
Lingling TieCollege of Veterinary Medicine, Xinjiang Agricultural University, Ürümqi, People's Republic of China.
Zaib Ur RehmanDepartment of Poultry Science, Faculty of Veterinary and Animal Sciences, PMAS-Arid Agriculture University, Rawalpindi, Pakistan.
Xiaolong GaoCollege of Agriculture and Animal Husbandry, Qinghai University, Xining, People's Republic of China.
Huibao WangSchool of Environment Engineering, Gansu Forestry Voctech University, Tianshui, People's Republic of China.
Yu HanCollege of Advanced Agricultural Sciences, Yulin University, Yulin, People's Republic of China.
Xiangwei WangState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.
Xiangping YinState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.
Yuefeng SunState Key Laboratory for Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, People's Republic of China.ORCID 0009-0001-7976-0605
Jinxin Xie *College of Veterinary Medicine, Xinjiang Agricultural University, Ürümqi, People's Republic of China.ORCID 0000-0003-4772-7162
Shanhui Ren *College of Veterinary Medicine, Xinjiang Agricultural University, Ürümqi, People's Republic of China.ORCID 0000-0002-3065-2355

Funding

National Natural Science Foundation of China 32373027Natural Science Foundation of Gansu Province 24JRRE011Sanya Yazhou Bay Science and Technology City (YZBSTC) JL23YCKY01
6 · The paper itself

Abstract

Peste des petits ruminants (PPR) is a highly contagious viral disease that primarily affects sheep and goats, posing a significant threat to small ruminant livestock production. The protective humoral immunity against Peste des petits ruminants virus (PPRV) is mainly mediated by the hemagglutinin-neuraminidase (HN) glycoprotein. To elucidate the functional antigenic determinants of the PPRV HN protein, we developed a new monoclonal antibody (mAb), HN

Indexed as

Antibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralHN ProteinPeste-des-Petits-RuminantsPeste-des-petits-ruminants virusAnimalsEpitope MappingEpitopesGoatsMiceNeutralization TestsReceptors, VirusSheepAntibodies, MonoclonalAntibodies, NeutralizingAntibodies, ViralEpitopesHN ProteinReceptors, Virusantigenic epitopehemagglutinin–neuraminidaseneutralizing antibodypeste des petits ruminants virusreceptor interactionviral adsorption

Identifiers

PMID42383740
PMCPMC13386946

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.