Evidence map›Paper›PMID 42383484›Full record

ArticleJournal of pediatric gastroenterology and nutrition2026

Abdominal pain in pediatric immunoglobulin A vasculitis: Risk factors and severity predictors in a multicenter cohort.

Francisco Hugo Rodrigues Gomes, Natalia Maronese, Leticia Lizardo Magalhaes, Davi Casale Aragon, Gleice Clemente, Maria Teresa Terreri, Claudio Arnaldo Len, Rozana Gasparello de Almeida, Marta Cristine Felix Rodrigues, Flavio Sztajnbok and 5 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Francisco Hugo Rodrigues GomesDivision of Pediatric Rheumatology, Department of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.ORCID https://orcid.org/0000-0001-6354-824X
Natalia MaroneseDivision of Pediatric Rheumatology, Department of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.ORCID https://orcid.org/0000-0002-4755-1518
Leticia Lizardo MagalhaesDivision of Pediatric Rheumatology, Department of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.ORCID https://orcid.org/0009-0002-4936-5900
Davi Casale AragonDivision of Pediatric Rheumatology, Department of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.ORCID https://orcid.org/0000-0003-1019-3654
Gleice ClementePediatric Rheumatology Unit, Universidade Federal de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-7824-437X
Maria Teresa TerreriPediatric Rheumatology Unit, Universidade Federal de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-2496-4296
Claudio Arnaldo LenPediatric Rheumatology Unit, Universidade Federal de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-8636-1744
Rozana Gasparello de AlmeidaRheumatology Division, Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-2570-8158
Marta Cristine Felix RodriguesRheumatology Division, Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0001-6787-3824
Flavio SztajnbokRheumatology Division, Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-7301-9664
Lia Vineyard SteuerPediatric Rheumatology Unit, Instituto da Criança e do Adolescente, Hospital das Clínicas HCFMUSP, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-0828-1949
Matheus Santos FrançaPediatric Rheumatology Unit, Instituto da Criança e do Adolescente, Hospital das Clínicas HCFMUSP, São Paulo, Brazil.ORCID https://orcid.org/0009-0009-5430-0088
Clovis Artur Almeida da SilvaPediatric Rheumatology Unit, Instituto da Criança e do Adolescente, Hospital das Clínicas HCFMUSP, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-9250-6508
Virginia Paes Leme FerrianiDivision of Pediatric Rheumatology, Department of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.ORCID https://orcid.org/0000-0002-9555-9389
Luciana Martins de CarvalhoDivision of Pediatric Rheumatology, Department of Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.ORCID https://orcid.org/0000-0002-0114-2735

Funding

Fundação de Apoio ao Ensino, Pesquisa e Assistência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FAEPA-HCFMRP-USP)
6 · The paper itself

Abstract

objectivesTo identify risk factors for abdominal pain and predictors of complicated abdominal pain in pediatric immunoglobulin A vasculitis (IgAV).

methodsRetrospective multicenter study including children and adolescents (≤18 years) fulfilling the European League Against Rheumatism/Pediatric Rheumatology International Trials Organization/Pediatric Rheumatology European Society (EULAR/PRINTO/PRES) criteria for IgAV and followed at four tertiary centers in Brazil. Factors associated with abdominal pain in the overall cohort and with complicated abdominal pain (defined as abdominal pain associated with intussusception, intestinal bleeding, or acute abdomen) were evaluated during the first 3 months of the disease and at the end of follow-up. Univariate analyses, a pre-specified multivariable log-binomial regression model, and receiver operating characteristic (ROC) curve analysis were performed.

resultsAmong the 687 pediatric patients with IgAV, 420 (61.1%) developed abdominal pain within the first 3 months and 428 (62.3%) by the end of follow-up (median follow-up of 54.1 months [interquartile range 50.7-59.3]). Among patients with abdominal pain, 22.2% developed complications. Prolonged purpuric/petechial rash (>29 days; RRadj 1.78, 95% confidence interval [CI] 1.09-2.91) and leukocytosis (>13,500/mm

conclusionProlonged purpuric/petechial rash and leukocytosis were independently associated with complicated abdominal pain. Leukocytosis may help identify children at higher risk of acute abdomen.

Indexed as

Abdominal PainIgA VasculitisAdolescentBrazilChildChild, PreschoolFemaleFollow-Up StudiesGastrointestinal HemorrhageHumansIntussusceptionMaleRetrospective StudiesRisk FactorsROC CurveSeverity of Illness Indexabdomen, acutegastrointestinal diseasesHenoch–Schonlein purpuraintussusceptionleukocytosis

Identifiers

PMID42383484
PMCPMC13539643

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.