Evidence map›Paper›PMID 42383341›Full record

ArticleFuture oncology (London, England)2026

Healthcare resource utilization and economic burden of metastatic pancreatic cancer: a US commercial and Medicare claims analysis.

Rupali Fuldeore, Adaeze Q Amaefule, Gergana Georgieva, Tomomi Kimura, Baoguo Jiang, Kenneth H Yu

Abstract read
In one paragraph

Article in Future oncology (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rupali FuldeoreUS Value Evidence, Astellas Pharma Global Development Inc., Northbrook, IL, USA.
Adaeze Q AmaefuleUS Value Evidence, Astellas Pharma Global Development Inc., Northbrook, IL, USA.
Gergana GeorgievaUS Medical Affairs, Astellas Pharma Global Development Inc., Northbrook, IL, USA.
Tomomi KimuraReal World Data Science, Astellas Pharma Global Development Inc., Northbrook, IL, USA.
Baoguo JiangReal World Data Science, Astellas Pharma Global Development Inc., Northbrook, IL, USA.
Kenneth H YuDavid M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

aimTo assess healthcare resource utilization (HRU) and costs among patients with metastatic pancreatic cancer (mPC). PATIENTS AND

methodsAdult US patients with an mPC diagnosis based on index date 1 January 2020-31 December 2022 were identified in the Merative MarketScan database. All-cause healthcare visits and costs (USD) were estimated per-person-per-month (PPPM) for 1 year post-index period. First-line (1L) treatments (≤90 days post-index) were categorized as FOLFIRINOX (leucovorin, fluorouracil, irinotecan, oxaliplatin)-based, gemcitabine+paclitaxel-based, other, or none.

resultsClaims from 2318 patients with mPC were included: 68.6% (1589/2318) with commercial and 31.4% (729/2318) with Medicare. Mean total costs PPPM were $34,215 with commercial and $15,158 with Medicare. A total of 25.7% (409/1589) of commercially insured patients and 43.2% (315/729) of Medicare-insured patients did not receive 1L treatment. Median (interquartile range) cumulative length of stay was 0.8 days (0.1-2.4) with commercial insurance and 0.7 days (0.0-2.4) with Medicare. All-cause PPPM costs were higher for patients without 1L treatment than with 1L treatment in both insurance types, primarily driven by inpatient and outpatient visits.

conclusionsPatients with mPC experienced high economic burden, mostly attributable to inpatient and outpatient costs. The high rate of patients with mPC not receiving 1L treatment merits further exploration.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsCost of IllnessHealth Care CostsMedicarePancreatic NeoplasmsPatient Acceptance of Health CareAgedFemaleHealth ResourcesHumansMaleMiddle AgedNeoplasm MetastasisUnited Statesclaims analysiseconomic burdenhealthcare costshealthcare resource utilizationMetastatic pancreatic cancer

Identifiers

PMID42383341
PMCPMC13374745

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.