Evidence map›Paper›PMID 42383320›Full record

ArticleClinical transplantation2026

Feasibility, Safety and Outcomes of Early Mobilization in the ICU Following Lung Transplantation: A Scoping Review.

Matthieu Reffienna, Adéla Foudhaïli, Jonathan Messika, Damien Vitiello

Abstract readScoping Review
In one paragraph

Article in Clinical transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthieu ReffiennaService De Réanimation polyvalente, Hôpital Foch, Suresnes, France.ORCID https://orcid.org/0000-0002-2046-166X
Adéla FoudhaïliUniversité Paris Cité, Inserm, MASCOT, Paris, France.ORCID https://orcid.org/0000-0001-5079-664X
Jonathan MessikaUniversité Paris Cité, Inserm, Centre de recherche sur l'inflammation, Paris, France.ORCID https://orcid.org/0000-0003-2123-3527
Damien VitielloUniversité Paris Cité, Institut des Sciences du Sport-Santé de Paris, Paris, France.ORCID https://orcid.org/0000-0003-3048-1880

Funding

SRLF-SKR research
6 · The paper itself

Abstract

backgroundLung transplantation (LTx) is performed in approximately 4500 patients worldwide each year. Postoperatively, patients are at high risk of muscle catabolism due to Intensive Care Unit (ICU)-acquired weakness, potentially compromising functional recovery. While post-LTx rehabilitation is usually initiated after hospital discharge, the feasibility and safety of early mobilization during the ICU stay remain unclear. This scoping review aimed to synthesize available evidence on the feasibility, safety, and outcomes of early mobilization initiated in the ICU following LTx.

methodsWe conducted a scoping review with comprehensive searches in MEDLINE (via PubMed), Embase, PEDro, Web of Science, CINAHL, Scopus, Cochrane CENTRAL, and PROSPERO. Study selection, data extraction, and analysis were performed independently by two reviewers.

resultsThe search identified 3219 records, of which 32 sources met inclusion criteria, including 17 original studies, three conference abstracts, four registered protocols, and eight narrative reviews. Despite marked heterogeneity in study designs, interventions, and outcomes, early mobilization was consistently reported as feasible and safe, with initiation possible within the first 24 h of ICU stay. Interventions were generally multimodal, progressive, and individualized. Adverse events were infrequently reported.

conclusionsEarly mobilization during the ICU stay following LTx appears feasible and safe, although the evidence is limited by the small number of studies and the predominance of low-level designs. Based on the available literature, we propose a preliminary mobilization framework tailored to this population. Further high-quality studies are required to confirm these findings and to evaluate clinical benefits.

trial registrationOpen Science Framework https://osf.io/nhr3e.

Indexed as

Early AmbulationIntensive Care UnitsLung TransplantationFeasibility StudiesHumansPrognosisintensive care unitlung transplantationmuscle atrophyphysiotherapyultrasonography

Identifiers

PMID42383320
PMCPMC13320722

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.