Evidence map›Paper›PMID 42383234›Full record

ArticleJournal of ophthalmology2026

Prognostic Value of Interocular Flicker ERG Asymmetry in Acute Postoperative Endophthalmitis After Intraocular Surgery: A Pilot Study.

Ying Zheng, Simon Dulz, Vasyl Druchkiv, Martin Stephan Spitzer, Christos Skevas

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying ZhengDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, uke.de.ORCID https://orcid.org/0000-0002-3741-0199
Simon DulzDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, uke.de.
Vasyl DruchkivDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, uke.de.ORCID https://orcid.org/0000-0002-6344-4480
Martin Stephan SpitzerDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, uke.de.
Christos SkevasDepartment of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, uke.de.ORCID https://orcid.org/0000-0002-4983-3228

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Objectives: Postoperative endophthalmitis remains a vision-threatening complication despite advances in treatment. Current prognostic markers (Gram stain and initial visual acuity) have limited predictive values for real-time retinal neuronal function assessment and visual recovery. The purpose of this pilot study was to explore whether photopic electroretinograms might be used to forecast the endophthalmitis prognosis following intravitreal injection or phacoemulsification intraocular lens implantation. Subjects/Methods: This prospective observational study included 11 consecutive patients with acute postoperative endophthalmitis following phacoemulsification with IOL implantation (3 eyes) or intravitreal injections (8 eyes). ERGs were recorded using a portable RETeval™ system under nonmydriatic conditions. R Core Team (2019) was used to assess the preoperative electroretinogram outcomes, duration until the onset of endophthalmitis, procedure types of original surgeries, and pre- and postoperative best-corrected visual acuity. Results: Mean patient age was 79.23 years (range 62-88). A significant correlation was found between interocular photopic flicker latency difference and BCVA improvement ( Conclusion: In this hypothesis-generating pilot study of acute postoperative endophthalmitis, a smaller interocular flicker ERG latency difference at presentation is associated with better visual recovery. These preliminary findings suggest that this rapid, noninvasive functional test may have potential as a prognostic biomarker and warrants further validation in larger cohorts, complementing existing clinical and microbiological parameters in the management of this sight-threatening infection.

Indexed as

electroretinographyendophthalmitisflicker ERGinflammationintraocular infectionprognosis

Identifiers

PMID42383234
PMCPMC13318480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.