ArticlePNAS nexus2026
Can AI help reduce prejudice? Evaluating the effectiveness of AI-powered personalized persuasion on support for transgender rights.
Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Large Language Model Chatbot Conversations vs Public Health Materials and Parental HPV Vaccination Intentions: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Can AI help reduce prejudice? Evaluating the effectiveness of AI-powered personalized persuasion on support for transgender rights.PNAS nexus · 2026Article
- Chatbot Voting Advice Applications inform but seldom sway young unaligned voters.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Personalized interpersonal conversations are among the most effective known tools for reducing prejudice, yet they are difficult to scale because they require skilled human facilitators. This study tests whether AI can approximate the effects of these interventions. Using OpenAI's GPT-4o, we developed a messaging-based intervention that engaged US participants in individualized, morally aligned dialogs about transgender rights. In a preregistered experiment, these AI-mediated conversations significantly increased support for transgender rights across multiple attitudinal measures. Robustness checks, including weighting and sensitivity analyses, confirmed the reliability of these effects, and analyses of the conversations support the idea that moral matching between the AI and participants played a key role in reducing prejudice. However, follow-up data collected 1 week later indicated that the attitudinal gains diminished over time, suggesting that reinforcement may be necessary to sustain change. Together, these findings indicate that generative AI can facilitate value-aligned dialog capable of shifting social attitudes, while highlighting the challenge of achieving meaningful durable impacts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.