Evidence map›Paper›PMID 42383226›Full record

ArticleToxicology reports2026

Genotoxicity of Carbohydrate Derived Fulvic Acid.

Stewart James Clark, Michael Graz

Abstract read
In one paragraph

Article in Toxicology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stewart James ClarkBiophys Limited, Unit 11, Cardiff Medicentre, Heath Park Way, Cardiff CF14 4UJ, United Kingdom.
Michael GrazBiophys Limited, Unit 11, Cardiff Medicentre, Heath Park Way, Cardiff CF14 4UJ, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Naturally derived and extracted fulvic acids have been used for immune modulation, antioxidant, diuretic, and antihypertensive applications for centuries. However, fulvic acid materials from the environment vary substantially in composition and may contain impurities such as heavy metals, increasing the toxicological risk to consumers when using these products. To overcome compositional variability and avoid environmental contaminants, carbohydrate-derived fulvic acid (CHD-FA) was developed by wet oxidation of sucrose using only molecular oxygen and water, and is manufactured under GMP via a patented process. To determine the genotoxicity of CHD-FA, we evaluated its potential toxicity using the OECD bacterial reverse mutation (Ames) test, the

Indexed as

Carbohydrate-Derived Fulvic AcidGenotoxicitySafety

Identifiers

PMID42383226
PMCPMC13316165

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.