ArticleEuropean journal of radiology open2026
Ultra-low contrast agent dosage in photon-counting CT angiography of the thoracoabdominal aorta.
Article in European journal of radiology open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To assess the viability of an ultra-low contrast agent protocol (ULC) for aortic photon-counting CT angiography (PCD-CTA). Materials and methods: For this retrospective, single-center study, 31 consecutive patients receiving PCD-CTA with 48 ml Imeron® 150mgI/ml (≙ 7.2 g iodine) were assessed. Virtual monoenergetic images with 45/55 keV were compared to a control sample scanned with radiation-dose-equivalent 55 keV protocols (120kVp; image-quality-level 42) employing standard (SC; 60 ml Imeron® 350mgI/ml ≙ 21 g iodine) and low contrast agent dose (LC; 40 ml Imeron® 350 mg/ml ≙ 14 g iodine). Luminal attenuation and image noise were measured, while contrast-to-noise ratios were calculated. Five radiologists rated overall image quality, luminal attenuation, and diagnostic confidence using a 5-point rating scale. Results: Radiation dose and body-mass-index did not differ significantly among groups ( Conclusion: Despite inferior contrast, aortic PCD-CTA with ultra-low contrast agent dosage at 45 keV allows for diagnostic image quality. The proposed scan protocol may hold potential for kidney protection in vulnerable patient groups.
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