Evidence map›Paper›PMID 42383131›Full record

ArticleIndian journal of sexually transmitted diseases and AIDS

Therapeutic efficacy of cryotherapy in genital warts: A case series with patient-reported outcomes.

Chittarvu Karishni, Muske Samskruthi, Muthu Priya, Chintagunta Sudha Rani

Abstract readCase Reports
In one paragraph

Article in Indian journal of sexually transmitted diseases and AIDS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Chittarvu KarishniDepartment of DVL, Gandhi Hospital and Medical College, Secunderabad, Telangana, India.
Muske SamskruthiDepartment of DVL, Gandhi Hospital and Medical College, Secunderabad, Telangana, India.
Muthu PriyaDepartment of DVL, Gandhi Hospital and Medical College, Secunderabad, Telangana, India.
Chintagunta Sudha RaniDepartment of DVL, Gandhi Hospital and Medical College, Secunderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genital warts are common benign lesions caused predominantly by human papillomavirus types 6 and 11 and are associated with significant psychosocial morbidity. Cryotherapy remains a widely used ablative modality, yet data on patient-reported outcomes in real-world settings remain limited. To evaluate the therapeutic efficacy, safety profile, and patient-reported outcomes of cryotherapy in the management of genital warts. A case series of seven treatment-naive patients with clinically and dermoscopically confirmed genital warts was analyzed. All patients underwent cryotherapy with a cryoprobe using two freeze-thaw cycles per session at 2-week intervals. Pain was assessed using the Visual Analogue Scale (VAS), and quality-of-life changes were measured using the Dermatology Life Quality Index (DLQI) before treatment and two weeks after the final session. Complete or near-complete clearance was achieved in 71.4% of patients after 1-2 sessions. Adverse effects occurred in 57.1%, predominantly procedural pain and transient hypopigmentation. DLQI scores improved markedly among patients with complete clearance, indicating significant psychosocial recovery, whereas incomplete responders-particularly immunocompromised individuals-showed minimal improvement. Recurrence occurred in 14% of cases. Cryotherapy is a safe, cost-effective, and efficacious first-line treatment for genital warts, especially in immunocompetent patients. Incorporating patient-reported outcomes such as DLQI and VAS provides a holistic assessment of therapeutic success and should be adopted routinely.

Indexed as

Cryotherapygenital wartspatient-reported outcomes

Identifiers

PMID42383131
PMCPMC13318345

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