ReviewIndian journal of sexually transmitted diseases and AIDS
The relationship between human papillomavirus subtype and persistence or recurrence of condyloma acuminata: A systematic review and meta-analysis.
Review in Indian journal of sexually transmitted diseases and AIDS. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Condyloma acuminata (CA), a human papillomavirus (HPV)-linked sexually transmitted infection, frequently persists or recurs, especially with high-risk (HR) strains. This systematic review and meta-analysis examine how specific HPV subtypes influence CA persistence/recurrence. We searched four databases (Science Direct, PubMed, Cochrane/CENTRAL, and Google Scholar) for relevant observational studies and randomized controlled trials (2005-2025). All meta-analytic statistics were processed using RevMan 5.4.1. Eight studies comprising a total of 1,070 subjects analyzed in this review demonstrated variable findings regarding the association between HPV subtypes and the persistence or recurrence of CA. The distribution of HPV types showed wide variability. The identified low-risk HPV (LR-HPV) subtypes included types 2, 6, 11, 27, 40, 42, 43, 44, 46, and 61, while the HR subtypes were 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 54, 56, 58, 59, 61, 66, 68, 69, and 70. In addition, 413 cases were reported without specific HPV type information from the studies analyzed. The meta-analysis showed a nonsignificant trend where HR HPV was linked to greater recurrence/persistence than LR-HPV (pooled OR 1.45, 95% CI: 0.81-2.61;
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