Evidence map›Paper›PMID 42383100›Full record

ReviewImmunoTargets and therapy2026

T Helper Cells and Cytokine Networks in the Immunopathogenesis of Multiple Sclerosis.

Simeon Ikechukwu Egba, Gavin Chibundu Ikechukwu, Chinenye Iheanyi Okereke, Innocent Ogheneovo Orhonigbe, Robert Ikechukwu Uroko, Okechukwu Paul Chima Ugwu

Abstract readReview
In one paragraph

Review in ImmunoTargets and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simeon Ikechukwu EgbaDepartment of Biochemistry, Kampala International University, Kampala, Uganda.ORCID 0000-0002-8442-8869
Gavin Chibundu IkechukwuDepartment of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.ORCID 0000-0003-1834-4517
Chinenye Iheanyi OkerekeDepartment of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.ORCID 0009-0004-0351-9550
Innocent Ogheneovo OrhonigbeDepartment of Biochemistry, Delta State University, Abraka, Delta State, Nigeria.ORCID 0009-0004-1048-0359
Robert Ikechukwu UrokoDepartment of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.ORCID 0000-0002-6154-3477
Okechukwu Paul Chima UgwuDepartment of Biochemistry, Kampala International University, Kampala, Uganda.ORCID 0000-0003-3563-3521

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is a chronic autoimmune disorder of CNS with demyelination, neurodegeneration and compartmentalized inflammatory disorder. Excessive T-helper cell (CD4

Indexed as

autoimmunitycentral nervous systemcytokineshelper-inducermultiple sclerosisneuroinflammatory diseasesT-Lymphocytes

Identifiers

PMID42383100
PMCPMC13316819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.