Evidence map›Paper›PMID 42383049›Full record

ArticleFrontiers in medicine2026

Case Report: Similar STR profiles in non-twin siblings complicating chimerism analysis after allogeneic hematopoietic stem cell transplantation.

Amro A Filfilan, Mohieldin Elsayid, Meaad Almowaled, Naif S Sannan, Waseem Alzamzami, Doaa Alamoudi, Modhi Khamis, Dania A Monagel

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amro A FilfilanClinical Laboratory Sciences Program, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Mohieldin ElsayidClinical Laboratory Sciences Program, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Meaad AlmowaledClinical Laboratory Sciences Program, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Naif S SannanClinical Laboratory Sciences Program, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Waseem AlzamzamiDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia.
Doaa AlamoudiMinistry of National Guard-Health Affairs, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
Modhi KhamisMinistry of National Guard-Health Affairs, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
Dania A MonagelKing Abdullah International Medical Research Center, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fanconi anemia (FA) is an inherited bone marrow (BM) failure syndrome for which allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the only curative option. Short tandem repeat (STR) profiling is the reference molecular method for post-transplant chimerism monitoring, but its analytical performance depends on the presence of informative allelic differences between donor and recipient. We report a 3-year-old boy with FA carrying a homozygous FANCA c.2778 + 1G > A variant who underwent allo-HSCT from a human leukocyte antigen (HLA)-matched non-twin sibling donor. Pre-transplant STR analysis using two independent multiplex systems (PowerPlex

Indexed as

allogeneic hematopoietic stem cell transplantationcase reportchimerism monitoringconsanguinitydigital PCRfanconi anemianext-generation sequencingshort tandem repeat profiling

Identifiers

PMID42383049
PMCPMC13314465

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.