Evidence map›Paper›PMID 42383001›Full record

ArticleiScience2026

Yunhao Zhai, Min Wen Ku, Ka Yang, Aditya Patil, Pranav Prabhala, Liqun He, Yuncheng Man, Mizanur Rahman, Kavya Menon, Sven B Spörri and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Leveraging Microphysiological Systems to Facilitate Neutrophil-Based Cancer Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. New approach methodologies (NAMs) for preclinical and translational evaluation of mRNA-lipid nanoparticle (LNP) therapeutics.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Review
  3. Review
  4. Frontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Yunhao ZhaiWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Min Wen KuWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Ka YangDepartment of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Aditya PatilWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Pranav PrabhalaWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Liqun HeWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Yuncheng ManWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Mizanur RahmanWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Kavya MenonWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Sven B SpörriWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Supriya GharpureWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Abdul Rahman IsaacsWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Shay FerdosiGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Andrzej S PitekGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Giulietta MaruggiGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Sylvie BertholetGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Jessica FirestoneGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Kambiz MousaviGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Eric MillerGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Kate LuisiGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Caleb A HellmanCenter for Human Systems Immunology, Departments of Surgery and Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27701, USA.
LaTonya D WilliamsCenter for Human Systems Immunology, Departments of Surgery and Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27701, USA.
Georgia D TomarasCenter for Human Systems Immunology, Departments of Surgery and Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27701, USA.
Peng YinWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Steven P GygiDepartment of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Josie McAuliffeGSK, Rockville Center for Vaccine Research, Rockville, MD 20850, USA.
Donald E IngberWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.
Girija GoyalWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Predicting the efficacy and toxicity of mRNA vaccines remains challenging. We describe an

Indexed as

biological sciences

Identifiers

PMID42383001
PMCPMC13314794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.