Evidence map›Paper›PMID 42382838›Full record

ArticleClinical, cosmetic and investigational dermatology2026

Evolving Research Hotspots and Emerging Trends in Atopic Dermatitis and Inflammatory Bowel Disease: A Bibliometric Analysis.

Zhiquan Li, Chenwei Deng, Bingxuan Lu, Foling Chen, Xiyuan Cao, Jiwen Fan, Yu Song

Abstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhiquan LiClinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, People's Republic of China.ORCID 0009-0004-6208-1667
Chenwei DengClinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, People's Republic of China.
Bingxuan LuLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Foling ChenLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Xiyuan CaoLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.
Jiwen FanClinical Medical College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, People's Republic of China.
Yu SongLonghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The number of people affected by atopic dermatitis (AD) and inflammatory bowel disease (IBD) continues to rise, increasing the disease burden. These conditions are epidemiologically linked and share features related to barrier dysfunction, immune dysregulation, and microbial dysbiosis, making them an important focus of integrated research. However, systematic bibliometric analysis of this field remains lacking. This study aimed to characterize the publication landscape, knowledge structure, evolving hotspots, and emerging translational trends in AD-IBD research. Methods: English-language articles and reviews on the intersection of AD and IBD published between 2000 and 2025 were retrieved from the Web of Science Core Collection and Scopus. After merging, deduplication, and data standardization, CiteSpace, VOSviewer, and Scimago Graphica were used to analyze publication trends, country/region and institutional contributions, author and journal profiles, keyword co-occurrence, and co-cited references. Results: A total of 1,542 publications were included. Annual publication output increased steadily, with a marked acceleration after 2020. The United States ranked first in publication volume, total citations, and international collaboration strength, while Harvard University occupied a central position in the institutional collaboration network. The Journal of Allergy and Clinical Immunology ranked first in both citation and co-citation counts. Keyword clustering and co-cited reference burst analyses identified four major directions: gut microecology and immune regulation, shared inflammatory pathways and immune-mediated comorbidities, therapeutic strategies involving biologics and JAK inhibitors, and genetic susceptibility and causal inference. The field has gradually shifted from epidemiological associations and inflammatory mechanism exploration toward clinical translation and safety evaluation. Conclusion: AD-IBD research has evolved into a multidisciplinary field centered mainly in North America and Europe, with rapidly expanding contributions from Asia. Future studies should strengthen interdisciplinary and cross-regional collaboration and prioritize gut-skin axis mechanisms, stratified management of comorbid populations, and long-term risk-benefit assessment of targeted therapies.

Indexed as

atopic dermatitisbibliometricsgut–skin axisinflammatory bowel diseaseJAK inhibitorsvisual analysis

Identifiers

PMID42382838
PMCPMC13317777

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.