ArticleClinical, cosmetic and investigational dermatology2026
Evolving Research Hotspots and Emerging Trends in Atopic Dermatitis and Inflammatory Bowel Disease: A Bibliometric Analysis.
Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The number of people affected by atopic dermatitis (AD) and inflammatory bowel disease (IBD) continues to rise, increasing the disease burden. These conditions are epidemiologically linked and share features related to barrier dysfunction, immune dysregulation, and microbial dysbiosis, making them an important focus of integrated research. However, systematic bibliometric analysis of this field remains lacking. This study aimed to characterize the publication landscape, knowledge structure, evolving hotspots, and emerging translational trends in AD-IBD research. Methods: English-language articles and reviews on the intersection of AD and IBD published between 2000 and 2025 were retrieved from the Web of Science Core Collection and Scopus. After merging, deduplication, and data standardization, CiteSpace, VOSviewer, and Scimago Graphica were used to analyze publication trends, country/region and institutional contributions, author and journal profiles, keyword co-occurrence, and co-cited references. Results: A total of 1,542 publications were included. Annual publication output increased steadily, with a marked acceleration after 2020. The United States ranked first in publication volume, total citations, and international collaboration strength, while Harvard University occupied a central position in the institutional collaboration network. The Journal of Allergy and Clinical Immunology ranked first in both citation and co-citation counts. Keyword clustering and co-cited reference burst analyses identified four major directions: gut microecology and immune regulation, shared inflammatory pathways and immune-mediated comorbidities, therapeutic strategies involving biologics and JAK inhibitors, and genetic susceptibility and causal inference. The field has gradually shifted from epidemiological associations and inflammatory mechanism exploration toward clinical translation and safety evaluation. Conclusion: AD-IBD research has evolved into a multidisciplinary field centered mainly in North America and Europe, with rapidly expanding contributions from Asia. Future studies should strengthen interdisciplinary and cross-regional collaboration and prioritize gut-skin axis mechanisms, stratified management of comorbid populations, and long-term risk-benefit assessment of targeted therapies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.