ReviewFrontiers in immunology2026
Waldenström macroglobulinemia-associated renal AL amyloidosis: a case report and literature review.
Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Waldenström macroglobulinemia (WM) is a rare indolent B-cell lymphoma, characterized by lymphoplasmacytic infiltration of bone marrow and the existence of monoclonal IgM in circulation. Renal AL amyloidosis is an uncommon complication of WM, and its treatment is an enormous challenge to clinicians. This report describes a 71-year-old woman who presented with a 10-month history of recurrent bilateral lower extremity edema and a progressive fatigue. Physical and laboratory examinations revealed serum monoclonal IgMλ, nephrotic syndrome, moderate anemia and mild enlargement of bilateral inguinal superficial lymph nodes. Bone marrow aspiration demonstrated clonal lymphoplasmacytic infiltration, lymph node biopsy was consistent with lymphoplasmacytic lymphoma, and peripheral blood testing confirmed the presence of the
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