ReviewExploration (Beijing, China)2026
Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications.
Review in Exploration (Beijing, China), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastrointestinal (GI) perforation, as an acute digestive condition, is difficult to heal spontaneously and requires prompt surgical intervention or bioactive adhesives to promote wound closure. Among various types of tissue adhesives, hydrogel adhesives have attracted tremendous attention and have been used in the clinic due to their atraumatic nature, good biocompatibility, and tunable physicochemical properties. Despite their promise, the bioadhesive applications with engineered hydrogels still face challenges in the wet and acidic gastric environment. This review outlines the mainstream design approaches of hydrogel adhesives through covalent and noncovalent molecular interactions, illustrating the underlying adhesive mechanisms and material properties. Representative GI applications of hydrogel adhesives are also summarized. Finally, we discuss future perspectives on the clinical translations of hydrogel adhesives in the management of GI perforations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.