ArticleBasic and clinical neuroscience
Assessing Electrocardiographic Parameters in the Patients With Drug-resistant Temporal Lobe Epilepsy: A Case-control Study.
Article in Basic and clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Sudden, unexpected death in epilepsy (SUDEP) is a substantial cause of death in patients with epilepsy. Although electroconductive disorders leading to life-threatening arrhythmia are supposed to play a crucial role, there is a paucity of knowledge in variables among the patients with drug-resistant temporal lobe epilepsy (TLE) compared to the healthy controls. Methods: The current case-control study has been conducted on 50 drug-resistant TLE patients as the cases and 50 age- and gender-matched healthy subjects selected from their first-degree family members. Electrocardiographic (ECG) were taken from the cases when admitted at the hospital (baseline), immediately after a seizure incidence, and within an hour after the end of the seizure and compared with a random ECG of the controls considering parameters, including PR-, RR-, and corrected QT interval (QTc), P wave duration, and heart rate (HR) variability. Results: A shorter corrected QTc interval was notified among the drug-resistant TLE patients compared to the controls (P=0.017) in the baseline taken ECGs, while the assessments immediately after the seizure revealed significant differences in terms of RR-interval (P=0.005) and HR (P=0.005). Postictal ECGs did not differ between the groups (P>0.05). Conclusion: According to the findings of this study, shortened QTc interval at baseline ECGs, shortened RR interval, and increased HR during the seizure were the ECG elements that affected drug-resistant TLE patients; however, to generalize the outcomes, further studies are required.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.