ArticleHealth science reports2026
Outcomes and Predictors of Acute Post-Streptococcal Glomerulonephritis in Hospitalized Children in Northwest Ethiopia: A Multicenter Retrospective Cohort Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Acute post-streptococcal glomerulonephritis (APSGN) is one of the most critical health conditions. It remains an important cause of acute kidney injury, hospitalization, and long-term complications for children. Thus, this study aimed to assess the treatment outcome of APSGN and its predictors among pediatric patients at Comprehensive Specialized Hospitals in Northwest Ethiopia. Methods: An institutional retrospective cohort study was conducted on pediatric patients, reviewing medical records from admission to treatment outcome between September 01, 2018, and August 30, 2024. The collected data were entered using the Epi Data software (version 4.6.0.0) and exported to SPSS version 25.0. Adjusted odds ratio (AOR) with a corresponding 95% confidence interval (CI) and Results: Most patients with acute post-streptococcal glomerulonephritis demonstrated positive treatment outcomes, with 70.2% recovering completely. The majority of patients arrived at the hospital more than 2 weeks after infection, with 70.8% hospitalized for over 2 weeks. Children aged 5-9 years faced significantly higher odds of negative outcomes (AOR = 2.61, 95% CI: 1.34-5.10, Conclusion: The majority of patients with acute post-streptococcal glomerulonephritis recovered completely. Significant predictors of negative treatment outcomes included age, the evident source of infection, the duration of infection at admission, and the presence of acute kidney infection at admission. There should be a focus on treatment outcomes through thorough evaluation, follow-up, and monitoring.
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