ReviewRadiologia brasileira
The role of neuroimaging in the diagnosis of cerebral toxoplasmosis: a systematic review.
Review in Radiologia brasileira. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study presents a systematic review of the role of imaging in the diagnosis of central nervous system toxoplasmo-sis, in addition to a case series from a tertiary university hospital. The review was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines and registered in the International Prospective Register of Systematic Reviews (ID: CRD420251107718). Studies published after January 1, 2000 were retrieved from the PubMed, Embase, Scopus, and Latin-American and Caribbean Health Sciences Literature data-bases. Two authors, working independently, selected studies that met the eligibility criteria, which were organized with Rayyan software. Imaging findings were described using computed tomography (CT), conventional magnetic resonance imaging (MRI), advanced MRI sequences or nuclear imaging, focusing on single-photon-emission com-puted tomography, with and without thallium-201, and positron-emission tomography/CT. Extracted data focused on lesion topography, signal characteristics, enhancement, restricted diffusion, and when available, spectroscopy and perfusion MRI findings. To illustrate typical and atypical imaging features, a complementary case series was included, evaluating patients with confirmed cerebral toxoplasmosis. The review demonstrates that CT and MRI remain es-sential for diagnosis and follow-up, whereas advanced MRI sequences provide additional value in differentiating toxo-plasmosis from other opportunistic infections and neoplastic processes.
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