ReviewFrontiers in cellular and infection microbiology2026
Advances in mycobacteriophage research: from lytic mechanisms to one health applications.
Review in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Mycobacteriophages are viruses that specifically infect mycobacterial hosts. Owing to their ability to penetrate the unique and complex cell wall barrier of mycobacteria, mycobacteriophages have recently emerged as promising tools for the diagnosis and treatment of drug-resistant mycobacterial infections. This review systematically summarizes the classification, genomic features, lytic and lysogenic mechanisms of mycobacteriophages, as well as the intricate defense and counter - defense strategies between phages and their hosts. Furthermore, from a One Health perspective, we explore the diverse applications of mycobacteriophages across human health, animal health, and environmental management, including rapid detection, treatment of drug-resistant infections, environmental surveillance and occupational exposure management. Collectively, mycobacteriophages are promising for combating drug-resistant infections and playing an important role in integrated One Health strategies.
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