Evidence map›Paper›PMID 42382066›Full record

ArticleSmart molecules : open access2026

Carbon monoxide-triggered near-infrared photoacoustic-fluorescent integrated visualization tool for auxiliary diagnosis of heart failure and evaluation of reversal drug efficacy.

Hongze He, Jingrui Yang, Yu Wu, Ping Lin, Tianxiao Lai, Junjie Jia, Jiangfeng Li, Weiying Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Smart molecules : open access, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hongze HeInstitute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Special Biomedicine School of Medicine Guangxi University Nanning Guangxi China.
Jingrui YangInstitute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Special Biomedicine School of Medicine Guangxi University Nanning Guangxi China.
Yu WuInstitute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Special Biomedicine School of Medicine Guangxi University Nanning Guangxi China.
Ping LinInstitute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Special Biomedicine School of Medicine Guangxi University Nanning Guangxi China.
Tianxiao LaiInstitute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Special Biomedicine School of Medicine Guangxi University Nanning Guangxi China.
Junjie JiaInstitute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Special Biomedicine School of Medicine Guangxi University Nanning Guangxi China.
Jiangfeng LiInstitute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Special Biomedicine School of Medicine Guangxi University Nanning Guangxi China.
Weiying LinInstitute of Optical Materials and Chemical Biology Guangxi Key Laboratory of Electrochemical Energy Materials School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Special Biomedicine School of Medicine Guangxi University Nanning Guangxi China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF), a major global health challenge with high morbidity and mortality, lacks effective biomarkers and non-invasive tools for early diagnosis and therapy evaluation. Endogenous carbon monoxide (CO), a key biological signaling molecule, is closely linked to cardiovascular diseases such as HF when dysregulated. Integrating near-infrared (NIR) fluorescence (FL) imaging with photoacoustic (PA) imaging offers a powerful approach, as the 2D FL data can validate and supplement the 3D PA information for a more holistic disease assessment. Herein, we developed

Indexed as

carbon monoxidefluorescent imagingheart failurephotoacoustic imagingreversal of heart failure

Identifiers

PMID42382066
PMCPMC13317754

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.