ReviewJournal of traditional and complementary medicine2026
Damage-induced muscle regeneration after exercise in humans: Modulatory effects of ginsenoside Rg1.
Review in Journal of traditional and complementary medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
9 authors.
Funding
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Abstract
Exercise-induced focal sarcolemmal disruption in susceptible myofibers results in bone marrow cell infiltration and reduced cellular senescence in skeletal muscle, followed by increases in muscle strength and mass. In contrast, removal of gravitational loading during spaceflight or prolonged bed rest leads to rapid losses of muscle mass and strength, recapitulating features of ageing. Accumulating evidence indicates that this exercise-induced muscle adaptation is driven by damage-evoked immune signaling that mobilizes bone marrow-derived progenitor cells to sites of tissue injury for regeneration. Cross-age transplantation studies further demonstrate that circulating bone marrow-derived cells (i.e., immune and progenitor cells) are key determinants of muscle regenerative capacity. Recent human muscle biopsy studies reveal that infiltrating immune and progenitor cells can fuse with damaged myofibers and contribute mitochondria during recovery. Within this damage-induced regeneration framework, ginsenosides, the bioactive steroidal constituents of
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Registered trials
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