Evidence map›Paper›PMID 42381970›Full record

ArticleJournal of parasitology research2026

Evaluation of Imatinib and Its Combination With Albendazole Against

Zahra Hanifeh, Ali Haniloo, Negin Torabi, Mehdi Farhadi

Abstract read
In one paragraph

Article in Journal of parasitology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zahra HanifehDepartment of Parasitology and Mycology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, zums.ac.ir.ORCID https://orcid.org/0009-0008-8778-7550
Ali HanilooDepartment of Parasitology and Mycology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, zums.ac.ir.ORCID https://orcid.org/0000-0002-3200-3981
Negin TorabiDepartment of Parasitology and Mycology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, zums.ac.ir.ORCID https://orcid.org/0000-0001-5213-7015
Mehdi FarhadiDepartment of Parasitology and Mycology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran, zums.ac.ir.ORCID https://orcid.org/0000-0002-9138-0402

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Currently, benzimidazoles are the main drugs used for the treatment of hydatidosis. However, the available medications do not demonstrate the expected therapeutic efficacy. As a tyrosine kinase inhibitor, imatinib may interfere with parasite signaling pathways and exert antiparasitic effects. The present study is among the first to evaluate imatinib in Materials and Methods: The effects of imatinib alone and in combination with albendazole were assessed on protoscoleces and microcysts over 33 and 15 days, respectively, and compared with albendazole monotherapy. The viability percentage of protoscoleces was determined using the eosin exclusion assay. Ultrastructural and morphological changes were evaluated using scanning electron microscopy and inverted microscopy. Results: Maximum protoscolicidal activity was observed at a concentration of 40 Conclusion: The findings of this study demonstrated that imatinib has a significant effect on the protoscoleces and larval cyst forms of

Indexed as

albendazoleEchinococcus granulosushydatid cystimatinibmicrocystprotoscoleces

Identifiers

PMID42381970
PMCPMC13317143

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.