Evidence map›Paper›PMID 42381950›Full record

ArticleJTCVS open2026

Outcomes of mitral valve repair in ischemic mitral regurgitation: A two-decade experience.

Lokeswara Rao Sajja, Gopichand Mannam, Aditya Koppula, Satya Bhaskara Raju Dandu, Satyendranath Pathuri, Venkata Satya Siva Saikiran Krishnamurthy, V Ramachandra Raju Pusapati, Ramesh Gudapati, Jyothsna Guttikonda, Sriramulu Sompalli

Abstract read
In one paragraph

Article in JTCVS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Lokeswara Rao SajjaDivision of Cardiothoracic Surgery, Star Hospitals, Hyderabad, India.
Gopichand MannamDivision of Cardiothoracic Surgery, Star Hospitals, Hyderabad, India.
Aditya KoppulaDivision of Clinical Research in Cardiovascular Medicine/Surgery, Sajja Heart Foundation, Hyderabad, India.
Satya Bhaskara Raju DanduDivision of Cardiothoracic Surgery, Star Hospitals, Hyderabad, India.
Satyendranath PathuriDivision of Cardiothoracic Surgery, Star Hospitals, Hyderabad, India.
Venkata Satya Siva Saikiran KrishnamurthyDivision of Cardiothoracic Surgery, Star Hospitals, Hyderabad, India.
V Ramachandra Raju PusapatiDivision of Clinical Research in Cardiovascular Medicine/Surgery, Sajja Heart Foundation, Hyderabad, India.
Ramesh GudapatiDivision of Cardiology, Star Hospitals, Hyderabad, India.
Jyothsna GuttikondaDivision of Clinical Research in Cardiovascular Medicine/Surgery, Sajja Heart Foundation, Hyderabad, India.
Sriramulu SompalliDivision of Cardiac Anaesthesiology, Star Hospitals, Hyderabad, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The study objective was to evaluate long-term survival outcomes after mitral valve repair in patients with moderate or moderate-to-severe ischemic mitral regurgitation undergoing concomitant coronary artery bypass grafting. Methods: We retrospectively analyzed 212 consecutive patients who underwent mitral valve repair with restrictive annuloplasty and concomitant coronary artery bypass grafting for ischemic mitral regurgitation and coronary artery disease at a tertiary center between January 2005 and May 2025. Survival at 1, 5, 10, 12, and 20 years was assessed using Kaplan-Meier estimates and Cox proportional hazard models. Differential survivals were compared using hazard ratios for the following variables: age more than 65 years, sex, diabetes, residual postoperative mitral regurgitation, incomplete revascularization, left ventricular ejection fraction less than 40%, left ventricular end-systolic diameter 45 mm or greater, and preoperative renal dysfunction (serum creatinine ≥1.5 mg/dL). Results: Of 212 patients, survival at 1, 5, 10, 12, and 20 years was 97.6%, 94.3%, 88.7%, 87.3%, and 81.1%, respectively. At 12 years, survival was significantly lower in patients with diabetes (82.1% vs 93% in nondiabetic patients; hazard ratio, 2.79 [1.18-6.61], Conclusions: This 2-decade experience shows that mitral valve repair with restrictive annuloplasty combined with coronary artery bypass grafting yields favorable long-term survival in moderate or moderate-to-severe chronic ischemic mitral regurgitation, particularly when residual mitral regurgitation is avoided, revascularization is complete, and preoperative left ventricular end-systolic diameter is less than 45 mm.

Indexed as

ischemic mitral regurgitationmitral valve repairsurvival analysis

Identifiers

PMID42381950
PMCPMC13316314

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.