Merkel Cell Carcinoma of the Hand.

Brooklyn VanDerWolde, Victoria Durkin, Kelly Jerstad, James Breit, Robert E Van Demark

Abstract readCase Reports

In one paragraph

Article in Journal of hand surgery global online, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brooklyn VanDerWoldeUniversity of South Dakota Sanford School of Medicine, Sioux Falls, SD.

Victoria DurkinDepartment of Graduate Medical Education, University of South Dakota Sanford School of Medicine, Sioux Falls, SD.

Kelly JerstadDepartment of Graduate Medical Education, University of South Dakota Sanford School of Medicine, Sioux Falls, SD.

James BreitDepartment of Graduate Medical Education, University of South Dakota Sanford School of Medicine, Sioux Falls, SD.

Robert E Van DemarkDepartment of Graduate Medical Education, University of South Dakota Sanford School of Medicine, Sioux Falls, SD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer, typically involving the head, neck, and rarely extremities. MCC of the hand is rare, and early diagnosis is critical to optimizing patient outcomes. We report a case of MCC of the hand in a 79-year-old woman with a 1-month history of a left-hand mass. A punch biopsy of the lesion confirmed the diagnosis of MCC. Treatment consisted of wide local excision with 1.5 cm margins, split-thickness skin grafting, a negative sentinel node biopsy, followed by a single treatment of adjuvant radiation therapy. This case emphasizes the importance of early detection of MCC in atypical locations and highlights the challenges in diagnosis and management. Early recognition and aggressive treatment of MCC is critical to improving patient outcomes. This case also discusses a change in adjuvant radiation therapy protocols for MCC.

Indexed as

Malignant skin cancerMerkel cell polyomavirusMerkel cell tumorNeuroendocrine tumorSingle-fraction radiation therapy

Identifiers

PMID42381854

DOI10.1016/j.jhsg.2026.101081

PMCPMC13314730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.