ArticleIndian journal of psychiatry2026
Modulating cue-induced craving in alcohol dependence syndrome: A functional magnetic resonance imaging blood oxygen level-dependent activation study of adjunctive cathodal high-definition transcranial direct current stimulation over the insula.
Article in Indian journal of psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cue-elicited craving is a major precipitant of relapse in alcohol dependence syndrome (ADS). High-definition transcranial direct current stimulation (HD-Tdcs) modulates craving circuits, while blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) maps brain activity to reveal addiction mechanisms. Aim: To compare the impact of cathodal HD-tDCS over the insula on cue-induced craving in ADS individuals, using changes in fMRI BOLD signal to measure individual differences in neural activation. Methodology: This study employed a randomized, double-arm, sham-controlled pre-post experimental design. Forty male ADS in-patients (18-50 years), diagnosed with ICD-10 DCR F10.24 and clinical institute withdrawal assessment for alcohol-revised (CIWA-Ar) <10, were assigned to active or sham HD-tDCS ( Result: Baseline characteristics did not show any significant differences between groups. After intervention, active HD-tDCS was associated with significant decreases in ACQ-NOW (217.1 ± 18.38 to 122.2 ± 46.7, Conclusion: Cathodal HD-tDCS over the insula could be an exciting adjunctive treatment for decreasing cue-induced craving in ADS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.