Evidence map›Paper›PMID 42381695›Full record

ArticleJournal of toxicology2026

Exposure to Heavy Metals Arsenic, Cadmium and Lead Exacerbates Carcinogenic and Noncarcinogenic Health Risks Among Diabetic and Hypertensive Patients.

Fombat Zenabou Mbebwoh, Muankang Junior Tegha Kum, Choumessi Tchewonpi Aphrodite, Kada Sanda Antoine, Fusi Christian Suh, Manfo Tsague Faustin Pascal, Nantia Akono Edouard

Abstract read
In one paragraph

Article in Journal of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fombat Zenabou MbebwohDepartment of Biochemistry, Faculty of Science, University of Bamenda, PO Box 39, Bambili, Cameroon, unibda.net.ORCID https://orcid.org/0009-0009-8459-9818
Muankang Junior Tegha KumDepartment of Biochemistry, Faculty of Science, University of Bamenda, PO Box 39, Bambili, Cameroon, unibda.net.ORCID https://orcid.org/0009-0000-6028-2829
Choumessi Tchewonpi AphroditeDepartment of Biochemistry, Faculty of Science, University of Bamenda, PO Box 39, Bambili, Cameroon, unibda.net.ORCID https://orcid.org/0000-0002-0962-3242
Kada Sanda AntoineDepartment of Zoology, Faculty of Science, University of Bamenda, PO Box 39, Bambili, Cameroon, unibda.net.ORCID https://orcid.org/0000-0001-5596-2862
Fusi Christian SuhDepartment of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, PO Box 63, Buea, Cameroon, ubuea.cm.ORCID https://orcid.org/0009-0000-1445-2823
Manfo Tsague Faustin PascalDepartment of Biochemistry and Molecular Biology, Faculty of Science, University of Buea, PO Box 63, Buea, Cameroon, ubuea.cm.ORCID https://orcid.org/0000-0002-7056-7817
Nantia Akono EdouardDepartment of Biochemistry, Faculty of Science, University of Bamenda, PO Box 39, Bambili, Cameroon, unibda.net.ORCID https://orcid.org/0000-0001-7013-2373

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to toxic metals contributes to the growing burden of noncommunicable diseases (NCDs), yet evidence from sub-Saharan Africa remains limited. This hospital-based cross-sectional study assessed heavy metal (arsenic [As], cadmium [Cd], lead [Pb]) exposure levels and their association with health risks in adult diabetic and hypertensive patients in Cameroon. It involved 178 participants (39 diabetics, 78 hypertensives, 61 comorbid), and the urinary metals were quantified using atomic absorption spectrophotometry and normalized to creatinine. Serum oxidative stress biomarkers including glutathione (GSH), thiobarbituric acid reactive substances (TBARS) and paraoxonase 1 (PON1) were measured. Health risk indices including estimated daily intake (EDI), chronic daily intake (CDI), hazard quotient (HQ), hazard index (HI) and cancer risk (CR), were computed. Proportion contribution trend (PCT), receiver operating characteristic (ROC) and ordinary least squares (OLS) regression were applied for risk and predictive analyses. Diabetic patients exhibited significantly higher (

Indexed as

diabetesheavy metalshypertensionoxidative stresspredictive analysisrisk assessment

Identifiers

PMID42381695
PMCPMC13318474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.