Evidence map›Paper›PMID 42381690›Full record

ArticleJDS communications2026

Effects of an electrolyte, energy, and osmolyte compound and heat stress on productivity in early-lactation Holstein cows.

D Onan-Martinez, C Nelson, F T Saputra, A Fraz, C Law, J Lance, H Olmo, I M Toledo, L T Casarotto, Y Wen and 2 more

Abstract read
In one paragraph

Article in JDS communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

D Onan-MartinezDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
C NelsonDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
F T SaputraDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
A FrazDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
C LawDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
J LanceDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
H OlmoDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
I M ToledoDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
L T CasarottoDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
Y WenDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.
N C UpahTechMix LLC, Stewart, MN 55385.
G E DahlDepartment of Animal Sciences, University of Florida, Gainesville, FL 32608.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heat stress affects milk production and intake of dairy cattle. Strategies to mitigate the effects of heat stress suggest dietary supplements including electrolyte, energy, and osmolyte compounds (such as Bovine BlueLite, TechMix, Stewart, MN, which is a blend of these compounds), but direct and long-term evaluation of this supplement in lactating cows is needed. We hypothesized that the supplement would improve productivity of dairy cows (∼52 DIM) under heat stress. Cows (n = 52) were enrolled into a 4-wk 2 × 2 factorial arrangement as follows: (1) heat stress control (HT-CON, n = 13), (2) heat stress plus supplement (HT-SUP, n = 13), (3) cooling control (CL-CON, n = 13), and (4) cooling plus supplement (CL-SUP, n = 13). Cows were housed in a freestall barn. Supplement treatment was top-dressed on TMR (56.5 g/cow in the morning and 56.5 g/cow in the afternoon feeding). Evaporative cooling was provided to cows in the cooling groups, whereas heat-stressed cows only had shade. Milk yield, DMI, rectal temperature (RT), and respiration rate (RR) of individual cows were recorded during the study. Furthermore, milk contents of fat, protein, and lactose were measured weekly. Heat stress increased RR and RT relative to the cooling groups. Heat stress reduced DMI (HT = 20.3, CL = 24.5 ± 0.4 kg/d; ± SE), and supplementation reversed some of the effects in heat-stressed cows (HT-SUP = 20.9, HT-CON = 19.6 ± 0.5 kg/d) but did not affect cooled cows. The ECM yield was also decreased by heat stress (HT = 38.1, CL = 42.6 ± 0.8 kg/d), and supplementation partially reversed that effect in HT-SUP relative to HT-CON (HT-SUP = 39.6, HT-CON = 36.5 ± 1.1 kg/d). No main effects were observed for milk components, cortisol, or heat shock protein plasma concentration. Results suggest that supplementation partially mitigated the effects of heat stress on DMI and ECM in lactating dairy cows.

Identifiers

PMID42381690
PMCPMC13316524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.