Evidence map›Paper›PMID 42381679›Full record

ArticleJDS communications2026

Effects of breed and colostrum replacer quantity on lymphocyte populations in the blood of Holstein and Holstein

M Kovacs, H McCarthy, T Chapelain, L Rostoll Cangiano, D L Renaud, M A Steele

Abstract read
In one paragraph

Article in JDS communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M KovacsDepartment of Animal Biosciences, Animal Science and Nutrition, University of Guelph, Guelph, ON, Canada N1G 1Y2.
H McCarthyDepartment of Animal Biosciences, Animal Science and Nutrition, University of Guelph, Guelph, ON, Canada N1G 1Y2.
T ChapelainDepartment of Animal Biosciences, Animal Science and Nutrition, University of Guelph, Guelph, ON, Canada N1G 1Y2.
L Rostoll CangianoDepartment of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, WI 53706.
D L RenaudDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada N1G 1Y2.
M A SteeleDepartment of Animal Biosciences, Animal Science and Nutrition, University of Guelph, Guelph, ON, Canada N1G 1Y2.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to explore the effects of breed and colostrum replacer (CR) quantity fed at birth on lymphocyte populations in the peripheral blood of Holstein (H) and Holstein × Angus (C) crossbred calves. Male H (n = 10) and C (n = 10) calves were enrolled immediately after birth and randomly assigned to one of 2 quantities of CR: low (2.5 g of IgG/kg of birth BW; n = 4 for H and 6 for C) or high (5.0 g of IgG/kg of birth BW; n = 6 for H and 4 for C). Calves were tube fed CR meals at 0 and 12 h and then fed milk replacer at an average of 12% of BW for 21 d, followed by an average of 15% of BW until gradual weaning, which occurred between d 49 and 70. Additionally, the calves had ad libitum access to both fresh water and calf starter. Fecal consistency and respiratory health were evaluated twice daily to monitor health status. Blood was collected and analyzed at 24 h using radial immunodiffusion to evaluate serum IgG concentrations. Additional blood samples were collected on d 14, 35, and 84 of life for lymphocyte isolation and staining with monoclonal antibodies against gamma delta T cell receptor, WC1.1, WC1.2, IgM, CD21, and CD32 and analyzed by flow cytometry. Serum IgG was greater for the calves fed greater quantities of CR, but there were no differences between breeds. The proportion of lymphocytes among the peripheral blood mononuclear cells tended to be greater for H calves, whereas the proportion of IgM

Identifiers

PMID42381679
PMCPMC13316472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.