Evidence map›Paper›PMID 42381527›Full record

ArticleJournal of Korean medical science2026

Hyuk-Je Lee, Bora Yoon, Yun Jeong Hong, Jee Hyang Jeong, SangYun Kim, Min Jeong Wang, Seong Hye Choi, Ji Sun Ryu, Sungmin Kang, Kee Hyung Park and 1 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hyuk-Je LeeDepartment of Neurology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-9965-4626
Bora YoonDepartment of Neurology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-1135-3392
Yun Jeong HongDepartment of Neurology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea.ORCID https://orcid.org/0000-0002-4996-4981
Jee Hyang JeongDepartment of Neurology, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7945-6956
SangYun KimDepartment of Neurology, Seoul National University Bundang Hospital & Seoul National University College of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0002-9101-5704
Min Jeong WangRoa Neurology Clinic, Seongnam, Korea.ORCID https://orcid.org/0000-0001-7215-4883
Seong Hye ChoiDepartment of Neurology, Inha University College of Medicine, Incheon, Korea.ORCID https://orcid.org/0000-0002-0680-8364
Ji Sun RyuResearch and Development, PeopleBio Inc., Seongnam, Korea.ORCID https://orcid.org/0009-0004-8906-2837
Sungmin KangResearch and Development, PeopleBio Inc., Seongnam, Korea.ORCID https://orcid.org/0000-0002-3542-9777
Kee Hyung ParkDepartment of Neurology, College of Medicine, Gachon University Gil Medical Center, Incheon, Korea. khpark0813@gmail.com.ORCID https://orcid.org/0000-0001-6847-6679
Dong Won YangDepartment of Neurology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. neuroman@catholic.ac.kr.ORCID https://orcid.org/0000-0002-4733-7298

Funding

Korea Institute for Advancement of Technology P0018061Ministry of Health and Welfare HI18C0530
6 · The paper itself

Abstract

backgroundApolipoprotein E (

methodsWe retrospectively analyzed baseline data from the Cohort Study to Identify Predictors for the Clinical Progression to Mild Cognitive Impairment or Dementia from Subjective Cognitive Decline. Plasma levels of the amyloid beta (Aβ) 42/40 ratio, glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and phosphorylated tau (pTau) 181 were quantified using Single Molecule Array technology. We assessed predictive performance of plasma biomarkers for amyloid PET outcomes using receiver operating characteristic analysis and linear regression models.

resultsThe study included 104 participants, with 20

conclusionPlasma biomarkers exhibit differential predictive performance for amyloid pathology based on

trial registrationClinical Research Information Service Identifier: KCT0003397.

Indexed as

Apolipoprotein E4Apolipoproteins EBiomarkersCognitive DysfunctionPlaque, AmyloidAgedAlzheimer DiseaseAmyloid beta-PeptidesArea Under CurveFemaleGenotypeGlial Fibrillary Acidic ProteinHumansMaleMiddle AgedNeurofilament ProteinsAmyloid beta-PeptidesApolipoprotein E4Apolipoproteins EBiomarkersGlial Fibrillary Acidic Proteinneurofilament protein LNeurofilament ProteinsPeptide Fragmentstau ProteinsAlzheimer's DiseaseApolipoproteins EPlasma BiomarkerSubjective Cognitive Decline

Identifiers

PMID42381527
PMCPMC13320468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.