Evidence map›Paper›PMID 42381365›Full record

ArticleMedeniyet medical journal2026

Exploring the Link Between Bacterial Biofilm and Disease Severity in Cholesteatoma-Associated CSOM.

Marojahan Pandiangan, Masyita Gaffar, Riskiana Djamin, Andi Alfian Zainuddin, Rizalinda Sjahril, Muhammad Amsyar Akil

Abstract read
In one paragraph

Article in Medeniyet medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. First Report of a Multidrug-ResistantVeterinary sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marojahan PandianganHasanuddin University Hospital, Department of Otorhinolaryngology-Head and Neck Surgery, Makassar, Indonesia.ORCID 0009-0003-4507-5022
Masyita GaffarHasanuddin University Hospital, Department of Otorhinolaryngology-Head and Neck Surgery, Makassar, Indonesia.ORCID 0000-0002-0636-3334
Riskiana DjaminHasanuddin University Hospital, Department of Otorhinolaryngology-Head and Neck Surgery, Makassar, Indonesia.ORCID 0000-0002-4557-8880
Andi Alfian ZainuddinHasanuddin University Faculty of Medicine, Department of Public Health and Community Medicine, Makassar, Indonesia.ORCID 0000-0003-4436-3906
Rizalinda SjahrilHasanuddin University Faculty of Medicine, Department of Microbiology, Makassar, Indonesia.ORCID 0000-0002-4678-9372
Muhammad Amsyar AkilHasanuddin University Hospital, Department of Otorhinolaryngology-Head and Neck Surgery, Makassar, Indonesia.ORCID 0000-0001-8011-8292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Chronic suppurative otitis media (CSOM) with cholesteatoma is a potentially dangerous condition that can lead to extracranial and intracranial complications. Bacteria associated with CSOM cholesteatoma frequently produce biofilms, which contribute to antibiotic resistance and accelerate disease progression. Methods: This cross-sectional study was conducted at the tertiary teaching hospital of Hasanuddin University, its affiliated hospitals, and the Hasanuddin University Medical Research Center (HUM-RC) between March 2024 and April 2025. Patients diagnosed with CSOM cholesteatoma who underwent mastoidectomy were enrolled. Bacterial isolates obtained from cholesteatoma tissue were evaluated for biofilm formation using crystal violet staining. Data were analyzed using SPSS software. Results: A total of 49 patients were included: 46.9% male and 53.1% female; age range 9-66 years. Of the bacterial isolates, 40 demonstrated biofilm formation. Conclusions: Biofilm formation was detected in the majority of bacterial isolates, with

Indexed as

biofilmcholesteatomaCSOM

Identifiers

PMID42381365
PMCPMC13320350

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.