Evidence map›Paper›PMID 42381286›Full record

ArticleJournal of the American Chemical Society2026

Enzyme-Responsive Chemiluminescent Probes Assembled with Iridium(III) Photosensitizers via Host-Guest Chemistry for Chemiluminescence-Induced Photodynamic Therapy.

Jia-Hao Wang, Lawrence Cho-Cheung Lee, Alex Man-Hei Yip, Justin Shum, Qi-Hang Cheng, Eunice Chiu-Lam Mak, Kenneth Kam-Wing Lo

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jia-Hao WangDepartment of Chemistry, City University of Hong Kong, Tat Chee Avenue, Hong Kong, P. R. China.
Lawrence Cho-Cheung LeeDepartment of Chemistry, City University of Hong Kong, Tat Chee Avenue, Hong Kong, P. R. China.ORCID 0000-0002-5046-0676
Alex Man-Hei YipDepartment of Chemistry, City University of Hong Kong, Tat Chee Avenue, Hong Kong, P. R. China.ORCID 0000-0002-2436-3047
Justin ShumDepartment of Chemistry, City University of Hong Kong, Tat Chee Avenue, Hong Kong, P. R. China.ORCID 0000-0001-5080-0792
Qi-Hang ChengDepartment of Chemistry, City University of Hong Kong, Tat Chee Avenue, Hong Kong, P. R. China.
Eunice Chiu-Lam MakDepartment of Chemistry, City University of Hong Kong, Tat Chee Avenue, Hong Kong, P. R. China.ORCID 0000-0002-5011-6971
Kenneth Kam-Wing LoDepartment of Chemistry, City University of Hong Kong, Tat Chee Avenue, Hong Kong, P. R. China.ORCID 0000-0002-2470-5916

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) is effective for localized cancers, but its reliance on external light limits treatment depth and uniformity. Herein, we report a programmable supramolecular chemiluminescence (CL)-induced PDT platform that generates reactive oxygen species (ROS) in the absence of light irradiation and displays intrinsic cancer selectivity. This platform is constructed through the supramolecular interaction between enzyme-responsive chemiluminescent spiroadamantyl phenoxy-1,2-dioxetane probes (

Indexed as

Antineoplastic AgentsCoordination ComplexesIridiumLuminescent AgentsPhotochemotherapyPhotosensitizing AgentsAnimalsHeLa CellsHumansLuminescenceMolecular StructureReactive Oxygen SpeciesAntineoplastic AgentsCoordination ComplexesIridiumLuminescent AgentsPhotosensitizing AgentsReactive Oxygen Species

Identifiers

PMID42381286
PMCPMC13383634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.