Evidence map›Paper›PMID 42381005›Full record

ArticleBMC veterinary research2026

Spatial distribution and determinants of antimicrobial resistance in livestock across pathogen types, animal species and antimicrobial classes.

Rodiat Olabisi Omotoso, Ismail Ayoade Odetokun, Aminu Shittu, Mahmoud Elthoth, Adebowale Olusola Adejumo

Abstract read
In one paragraph

Article in BMC veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rodiat Olabisi OmotosoDepartment of Statistics, Faculty of Physical Sciences, University of Ilorin, Ilorin, Nigeria. omotosorodiatolabisi@gmail.com.
Ismail Ayoade OdetokunDepartment of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Ilorin, Ilorin, Nigeria.
Aminu ShittuDepartment of Theriogenology and Animal Production, Faculty of Veterinary Medicine, Quantitative Epidemiology and Animal Health (QuantEpi-AH) Research Group, Usmanu Danfodiyo University, Sokoto, Nigeria.
Mahmoud ElthothDepartment of Health Studies, Royal Holloway University of London, Egham, TW20 0EX, UK.
Adebowale Olusola AdejumoDepartment of Statistics, Faculty of Physical Sciences, University of Ilorin, Ilorin, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) in livestock is a growing global health concern with important implications for food security, human and animal health. However, the spatial distribution and determinants of AMR in livestock systems remain insufficiently characterised. This study examined spatial patterns and contributions of selected AMR drivers in livestock AMR, using data from the ResistanceBank database, which encompasses livestock species, bacterial pathogens, and antimicrobial categories. This study included all data compiled in the Resistancebank database, including prevalence studies published between 2000 and 2021 and 33,186 resistance data points compiled from 93 countries. Spatial dependence was evaluated using Global and Local Moran's I statistics, while the influence of livestock species, pathogens, and antimicrobial classes was analysed using beta regression and Extreme Gradient Boosting (XGBoost) machine learning models. The spatial analysis includes only countries listed in the Resistancebank database and displays them. Global Moran's I revealed significant positive spatial autocorrelation in AMR proportions (I = 0.1911, p = 0.0246; Z-score = 1.9676, expected I = - 0.0127), indicating geographic clustering of resistance. High-high clusters were identified across South and East Asia, the Middle East, parts of Sub-Saharan Africa, and South America, whereas low-low clusters occurred in Southern Africa, Southeast Asia, and several European regions. Beta regression showed that cattle (β = -0.5953, p = 0.0263) and sheep (β = -0.7873, p = 0.0034) contributed less to AMR variation than buffalo, whereas highly important antimicrobials were associated with increased proportions of resistance (β = 0.3365, p < 0.0001). The XGBoost model demonstrated slightly better predictive performance (Root Mean Squared Error (RMSE) = 0.3428) than beta regression (RMSE = 0.3471). These findings reveal pronounced spatial clustering of AMR in livestock and underscore the need for strengthened global surveillance, improved antimicrobial stewardship and integrated One Health strategies to mitigate the spread of AMR.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialLivestockAnimalsBacteriaBoosting Machine Learning AlgorithmsCattleDatabases, FactualSpatial AnalysisAnti-Bacterial AgentsAntimicrobial resistanceAntimicrobial surveillanceLivestock productionMachine learningOne HealthSpatial analysisZoonotic pathogens

Identifiers

PMID42381005
PMCPMC13599096

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.