Evidence map›Paper›PMID 42380947›Full record

ArticleInfectious diseases of poverty2026

Spatiotemporal trends in tuberculosis incidence in Thailand, 2012-2023: a nationwide, province-level analysis.

Kittipong Sornlorm, Roshan Kumar Mahato, Sarayu Muntaphan, Kanit Hnuploy, Rajitra Nawawonganun

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Article in Infectious diseases of poverty, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kittipong SornlormFaculty of Public Health, Khon Kaen University, Khon Kaen, Thailand.
Roshan Kumar MahatoFaculty of Public Health, Khon Kaen University, Khon Kaen, Thailand.
Sarayu MuntaphanKhon Kaen Provincial Health Office, Khon Kaen, Thailand.
Kanit HnuployFaculty of Science and Technology, Suratthani Rajabhat University, Surat Thani, Thailand.
Rajitra NawawonganunFaculty of Public Health, Khon Kaen University, Khon Kaen, Thailand. rajina@kku.ac.th.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis (TB) remains a major public health challenge in Thailand, a high-burden country undergoing both epidemiological transition and pandemic-related disruption. This study examined temporal and spatial patterns of age-standardized TB incidence from 2012 to 2023 across Thailand's 13 health regions and 77 provinces.

methodsThis nationwide ecological study used annual TB case notifications (2012-2023) for all 77 Thai provinces from Thailand's National Disease Surveillance System (Report 506), Bureau of Epidemiology, with mid-year and age-stratified provincial populations. Age-standardized incidence rates (ASR) were calculated using the WHO World Standard Population (2000-2025). Temporal trends were assessed by Joinpoint regression with Bayesian-Information-Criterion model selection (maximum 2 joinpoints) and validated by generalized additive models. Spatial clustering was evaluated by Global Moran's I and Local Indicators of Spatial Association (LISA) under queen contiguity, with sensitivity analyses across alternative weights and Benjamini-Hochberg false-discovery-rate correction. Provinces were classified into long-term trend categories combining effect size (AAPC) and significance, and COVID-19 impact was quantified by 2019-2023 ASR percent change.

resultsNational TB incidence declined substantially from 2012 to 2023, although marked regional heterogeneity persisted. Five health regions showed the strongest long-term reductions: region 3 [AAPC: - 20.51, 95% confidence interval (CI): - 33.00 to - 13.77], region 9 (- 19.42, 95% CI: - 28.98 to - 8.57), region 4 (- 17.53, 95% CI: - 23.64 to - 12.89), region 11 (- 11.79, 95% CI: - 22.16 to - 0.04), and region 13 (- 11.19, 95% CI: - 22.44 to - 3.74). Region 6 showed an early decline followed by stabilisation, and region 12 showed a mid-period increase before a post-2019 reduction.

conclusionsThailand has achieved substantial overall reductions in TB incidence over the past decade, but pronounced regional and provincial disparities persist. Localized hot-spots, biphasic regional trajectories that may reflect surveillance and programmatic transitions, and compound vulnerability during the COVID-19 period underscore the need for geographically targeted monitoring, equitable resource allocation, and pro-poor interventions to sustain progress toward TB elimination.

Indexed as

TuberculosisBayes TheoremCOVID-19HumansIncidenceSpatio-Temporal AnalysisThailandDisease mappingEpidemiologyHealth policyJoinpoint regressionSpatiotemporal analysisThailandTuberculosis

Identifiers

PMID42380947
PMCPMC13321431

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.