Evidence map›Paper›PMID 42380788›Full record

Trial reportBMC neurology2026

The longer, the better? Investigating the effect of prolonged acoustic stimulation on brief acoustic tinnitus suppression.

Johanna Rischer, Patrick Neff, Berthold Langguth, Milena Engelke, Andreas Reissmann, Stefan Schoisswohl

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07472257 (Effects of Acoustic Stimulation Techniques on Tinnitus), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07472257 nacompletednot on this map

Effects of Acoustic Stimulation Techniques on Tinnitus

TypeinterventionalSponsorUniversity of RegensburgRan2018 to 2018Enrolled45ConditionsTinnitusArmsAcoustic Stimulation - 20 minutes, Acoustic stimulation - 3 minutes
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johanna RischerDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany. johanna.rischer@web.de.
Patrick NeffFaculty of Medicine, University of Zurich, Zurich, Switzerland.
Berthold LangguthDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Milena EngelkeDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Andreas ReissmannDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Stefan SchoisswohlDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrief acoustic tinnitus suppression following sound stimulation is being studied to better understand the mechanisms underlying tinnitus and short-term suppression of the tinnitus perception. In this context, several kinds of filtered or modulated stimuli have been investigated. However, little research was conducted regarding the effect of stimulation length for brief acoustic tinnitus suppression.

methodsThe aim of the present study was to compare the extent of tinnitus suppression after a 20-minute and a 3-minute acoustic stimulation with an individual best stimulus. Three experimental sessions were completed by 33 participants with chronic subjective tinnitus. In the first two sessions, eight different individualized, filtered, and/or amplitude-modulated stimuli were presented for 3 min each. For each participant, the stimulus which induced the strongest tinnitus loudness suppression (measured with a numeric rating scale in percent compared to baseline loudness) was chosen and then applied for 20 min in a third session.

resultsOn a group level, no significant difference in tinnitus loudness suppression comparing the 3-minute and the 20-minute acoustic stimulation using the individual best stimulus was observed. However, individual response patterns revealed great diversity as 12 participants showed better suppression after the 20-minute stimulation,12 experienced worse tinnitus suppression and for 9 participants no distinct change was evident compared to 3-minute acoustic stimulation.

conclusionsFuture research should try to characterize the subgroup of tinnitus patients that profits from prolonged acoustic stimulation and search for optimized simulation durations.

trial registrationThis trial was retrospectively registered on 2026/03/04 at ClinicalTrials.gov (ID: NCT07472257).

Indexed as

Acoustic StimulationTinnitusAdultAgedFemaleHumansLoudness PerceptionMaleMiddle AgedTime FactorsTreatment OutcomeAcoustic stimulationBrief acoustic tinnitus suppressionResidual inhibitionTinnitus

Identifiers

PMID42380788
PMCPMC13317285

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.